Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Microfluidic self-assembly of polymeric nanoparticles with tunable compactness for controlled drug delivery
TL;DR: In this article, the authors used microfluidics to control the local polymer concentration inside polymeric nanoparticles and demonstrated that the compactness of nanoparticles based on self-assembled hydrophobically modified chitosan (HMCs) biopolymer can be dictated with tunable rapid mixing via hydrodynamic flow focusing in micro-fluidic channels.
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Design and fabrication of hydrogel-based nanoparticulate systems for in vivo drug delivery
TL;DR: The latest advances in fabrication and engineering ofHydrogel nanoparticles are presented, and future avenues to enhance the potential of hydrogel-based nanoparticulate systems in treatment development and drug administration are illuminated.
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Synthesis of architecturally well-defined nanogels viaRAFT polymerization for potential bioapplications
Zesheng An,Qian Qiu,Guangyao Liu +2 more
TL;DR: The recent development in nanogel synthesis using preformed RAFT polymers and by direct RAFT polymerizations is reviewed.
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Nano-engineered electro-responsive drug delivery systems
TL;DR: This review will focus on this exciting and most recent direction taken in this field by first discussing drug delivery from electro-responsive films containing nano-scaled features, and then nanoscale dispersed/colloidal electro- responsive drug delivery systems, such as nanoparticles, micelles, and vesicular structures.
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Designing polymeric microparticulate drug delivery system for hydrophobic drug quercetin
TL;DR: The studies have revealed that when pure drug exhibits crystalline structure with less dissolution profile, formulated microparticles can help to obtain amorphous form of the same drug that is likely to have more dissolution property.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.