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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Polyacrylamide and methylcellulose hydrogel as delivery vehicle for the controlled release of paraquat pesticide

TL;DR: In this article, a semi-empirical model for the controlled release of paraquat pesticide from PAAm-MC hydrogels was proposed. But, the model was not applied to analyze the performance of the hydrogel-based vehicle.
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A Review: Tailor-made Hydrogel Structures (Classifications and Synthesis Parameters)

TL;DR: In this paper, a review highlights hydrogel structure and their different classifications under various heads and discusses various routes to obtain tailormade hydrogels by polymerizing a combination of two or more monomers with proper type of crosslinks.
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Enhanced antitumor effects by docetaxel/LL37-loaded thermosensitive hydrogel nanoparticles in peritoneal carcinomatosis of colorectal cancer.

TL;DR: Biodegradable and injectable thermosensitive PLA-L64-PLA hydrogel with lower sol–gel transition temperature at around body temperature and Doc+LL37 NPs–hydrogel significantly suppressed the growth of HCT116 peritoneal carcinomatosis in vivo and prolonged the survival of tumor-bearing mice.
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Biocompatible and degradable nanogels via oxidation reactions of synthetic thiomers in inverse miniemulsion

TL;DR: In this paper, the authors present synthesis and characterization of biocompatible and degradable nanogel carriers composed of thiol-functionalized polymers based on starshaped poly(ethylene oxide-statpropylene oxide) (sP(EO-stat-PO)) and linear poly(glycidol) (PG).
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Photoluminescent sensing hydrogel platform based on the combination of nanocellulose and S,N-codoped graphene quantum dots

TL;DR: In this paper, the authors reported the fabrication of a fluorescent hydrogel based on S,N-codoped Graphene Quantum Dots acting as luminophore and sensitizer.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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