Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Hydrogel: Preparation, characterization, and applications: A review
TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
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Chitosan-based hydrogels for controlled, localized drug delivery
TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
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Biomedical applications of hydrogels: A review of patents and commercial products
TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
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Journal ArticleDOI
Minimalism in fabrication of self-organized nanogels holding both anti-cancer drug and targeting moiety
Sungwon Kim,Kyong Mi Park,Jin Young Ko,Ick Chan Kwon,Hyeon Geun Cho,Dongmin Kang,In Tag Yu,Kwangmeyung Kim,Kun Na +8 more
TL;DR: A simplest strategy to fabricate nano-carriers to deliver doxorubicin (DOX) was proposed and successfully verified, to suggest a new method overcoming the complications in the drug carrier design.
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Synthesis and self-assembly of chitosan-based copolymer with a pair of hydrophobic/hydrophilic grafts of polycaprolactone and poly(ethylene glycol)
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Thermo- and pH-sensitive comb-type grafted poly(N,N-diethylacrylamide-co-acrylic acid) hydrogels with rapid response behaviors
TL;DR: In this article, a macromonomer of thermo-sensitive poly(N,N-diethylacrylamide)-co-acrylic acid was synthesized by grafting PDEA chains with freely mobile ends onto the backbone of a cross-linked (PDEA-co-AA) network.
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A novel wound dressing with an antibiotic delivery system stimulated by microbial infection.
Yoshihisa Suzuki,Masao Tanihara,Yoshihiko Nishimura,Kyoko Suzuki,Yoshimi Kakimaru,Yasuhiko Shimizu +5 more
TL;DR: A new type of wound dressing with controlled release of antibiotics only in the presence of inflection is developed, a drug delivery system in which gentamicin is bound to polyvinylalcohol hydrogel through an enzymatically degradable peptide linker containing a -(D)-Phe-Pro-Arg- sequence.
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Applications of biomimetic systems in drug delivery.
TL;DR: This review article highlights recent activities in the field of biomimetic systems and their application in controlled drug delivery, with a focus on synthesis and assembly for the creation of novel biomaterials.