Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Hydrogel: Preparation, characterization, and applications: A review
TL;DR: A review of the literature concerning classification of hydrogels on different bases, physical and chemical characteristics of these products, and technical feasibility of their utilization is presented in this paper, together with technologies adopted for hydrogel production together with process design implications, block diagrams, and optimized conditions of the preparation process.
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Chitosan-based hydrogels for controlled, localized drug delivery
TL;DR: The newest developments in chitosan hydrogel preparation are investigated and the design parameters in the development of physically and chemically cross-linked hydrogels are defined.
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Biomedical applications of hydrogels: A review of patents and commercial products
TL;DR: From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
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Regulated release of drug microspheres from inflammation responsive degradable matrices of crosslinked hyaluronic acid
TL;DR: In vivo implantation experiments revealed the quantitative degradation of the HA gel in response to inflammation, and crosslinked HA gels may be promising devices as inflammation (stimulus)-responsive degradable matrices for implantable drug delivery.
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Chitosan-TPP nanoparticle as a release system of antisense oligonucleotide in the oral environment.
TL;DR: The results suggest that the sustained release of oligonucleotide from chitosan nanoparticles may be suitable for the local therapeutic application in periodontal diseases.
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Irradiating or Autoclaving Chitosan/Polyol Solutions: Effect on Thermogelling Chitosan-β-glycerophosphate Systems
TL;DR: Polyols are potentially useful additive to maximise the viscoelastic and mechanical properties of chitosan-GP after steam sterilization.
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Gene delivery using temperature-responsive polymeric carriers.
TL;DR: Synthetic temperature-responsive polymers can be applied as gene carrier systems and strategy and clinical feasibility of the temperature- responsive vector system are discussed with an example of gene expression enhancement by temperature stimuli.
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Transdermal iontophoresis of sodium nonivamide acetate: V. Combined effect of physical enhancement methods
TL;DR: In this paper, the effect of iontophoresis combined with treatment of other physical enhancement methods such as electroporation, low frequency ultrasound, and erbium:YAG (yttrium-aluminum-garnet) laser on the transdermal delivery of sodium nonivamide acetate (SNA) was examined.