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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Atom transfer radical polymerization in inverse miniemulsion: A versatile route toward preparation and functionalization of microgels/nanogels for targeted drug delivery applications

TL;DR: Applications of atom transfer radical polymerization in inverse miniemulsion and disulfide–thiol exchange to prepare well-defined biodegradable functional nanogels (ATRP-nanogels), which have higher swelling ratios, better colloidal stability, and controlled degradation, are described.
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Evaluation of chitosan/γ-poly(glutamic acid) polyelectrolyte complex for wound dressing materials

TL;DR: In this paper, an easily stripped polyelectrolyte complex (PEC), which consists of chitosan as a cationic polyelectron and γ-poly (glutamic acid) (γ-PGA) as an anionic polyelectriclyte, was used as a wound dressing material.
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Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses.

TL;DR: The in vitro study showed that reducible AP-SS nanogels not only facilitated antigen uptake by mouse bone marrow dendritic cells (BMDCs), but also promoted intracellular antigen degradation and cytosolic release.
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Highly Conductive and Flexible Silver Nanowire-Based Microelectrodes on Biocompatible Hydrogel

TL;DR: It is anticipated that the AgNW-based microelectrodes on biocompatible hydrogel substrates can be a promising platform for realization of practical bioelectronics devices.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI

Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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