Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Cyclodextrin Mediated Controlled Release of Naproxen from pH-Sensitive Chitosan/Poly(Vinyl Alcohol) Hydrogels for Colon Targeted Delivery
TL;DR: It can be proposed that the deleterious effects of naproxen on the epithelium of the gastro-intestinal tract could be minimized by using the cyclodextrin containing hydrogels as drug delivery systems because they provide a controlled release resulting in a reduced concentration of free naproxin.
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Synthesis of kappa -carrageenan-g-poly(acrylamide)/sepiolite nanocomposite hydrogels and adsorption of cationic dye
TL;DR: In this article, nanocomposite hydrogels from grafting of acrylamide onto kappa-carrageenan biopolymer were prepared in the presence of sepiolite clay.
Journal ArticleDOI
Enhanced mechanical properties and gelling ability of gelatin hydrogels reinforced with chitin whiskers
TL;DR: In this paper, a gelatin/CHW nanocomposite hydrogels containing various concentrations of CHWs (0.25 − 1.0%, w/v) were successfully fabricated.
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Improving oral absorption via drug-loaded nanocarriers: absorption mechanisms, intestinal models and rational fabrication.
TL;DR: This review elucidates some considerable features of in vitro oral drug delivery in three different parts and embodies an in-depth discussion on the role of the intestinal absorption models used to predict permeability, cellular uptake or even toxicity of nanoparticles, resulting into the design of nanocarriers with optimum efficacy for oral delivery.
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In vivo evaluation of novel nanoparticles containing dexamethasone for ocular drug delivery on rabbit eye.
Farzaneh Rafie,Yousef Javadzadeh,Ali R. Javadzadeh,Leila Alizadeh Ghavidel,Behzad Jafari,Mohammad Moogooee,Soodabeh Davaran +6 more
TL;DR: In this article, a smart polymer loaded with dexamethasone on inflamed rabbit eye was used to investigate the in vivo effects of a new smart polymer load on ocular drug delivery using these novel micellar nanoparticles.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.