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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Citations
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Preparation of a Strong Gelatin-Short Linear Glucan Nanocomposite Hydrogel by an in Situ Self-Assembly Process.

TL;DR: An in situ self-assembly process for the preparation of gelatin-short linear glucan (SLG) nanocomposite hydrogels with enhanced mechanical strength and improved mechanical behavior is developed.
Journal ArticleDOI

Progress of polymer gels for conformance control in oilfield.

TL;DR: In this article, the authors discuss the polymer gel techniques from innovations to applications and discuss the related difficulties and future prospects of polymer gels, and provide a basis to develop polymer gel for future applications in oilfields to meet harsh reservoir conditions.
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Photochemical crosslinking of hyaluronic acid confined in nanoemulsions: towards nanogels with a controlled structure.

TL;DR: It is shown that HA precursors with polymerizable methacrylate groups (HA-MA) were highly biocompatible, stable under storage and enzymatically biodegradable, which opens the route for their application as drug delivery systems.
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Molecular dynamics simulation study of chitosan and gemcitabine as a drug delivery system.

TL;DR: Using molecular dynamics simulation, biodegradable biopolymer chitosan as a carrier for the drug gemcitabine was investigated and the effect of three initial drug concentrations on its loading efficiency was studied.
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Freeze-dried cylinders carrying chitosan nanoparticles for vaginal peptide delivery

TL;DR: In vitro release studies showed the ability of the sponge-like systems and chitosan nanoparticles to deliver the mucoadhesive nanoparticles and peptide respectively, and CLSM micrographs proved the nanoparticles ability promoting the peptide penetration inside the vaginal mucosa.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI

Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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