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Hydrogel Nanoparticles in Drug Delivery

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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.

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Polysaccharide-based micro/nanohydrogels for delivering macromolecular therapeutics.

TL;DR: This review outlines and critically evaluates the research findings on micro and nano-carrier polymeric hydrogels for the delivery of macromolecular therapeutics.
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Preparation and characterization of asiaticoside-loaded alginate films and their potential for use as effectual wound dressings

TL;DR: A wound dressing material was successfully prepared from alginate, a natural polymer capable of forming into hydrogels, and asiaticoside (PAC), a substance from the plant Centella asia which has commonly been used in traditional medicine to heal wounds as discussed by the authors.
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Designing hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract

TL;DR: This article focuses on the application of hydrogel particles for controlled or targeted release of lipophilic bioactive agents in the gastrointestinal tract including the mouth, stomach, small intestine, and colon.
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Strong and tough fully physically crosslinked double network hydrogels with tunable mechanics and high self-healing performance

TL;DR: In this paper, chitosan and poly(acrylic acid) (PAA) are employed as double networks (DN), and metal-coordination and chain entanglement are exploited as dual crosslinks to develop fully physically crosslinked DN hydrogels.
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Composite hydrogels based on gelatin, chitosan and polyvinyl alcohol to biomedical applications: a review

TL;DR: In this article, binary and ternary blends of chitosan, gelatin, and polyvinyl alcohol can lead to hydrogels that are unsuitable for biomedical applications.
References
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Journal ArticleDOI

Hydrogels for biomedical applications.

TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery

TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI

Hydrogels in pharmaceutical formulations.

TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article

Long-Circulating and Target-Specific Nanoparticles: Theory to Practice

TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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