Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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A robust platform for functional microgels via thiol-ene achemistry with reactive polyether-based nanoparticles.
Carolin Fleischmann,Jeffrey D. Gopez,Pontus Lundberg,Helmut Ritter,Kato L. Killops,Craig J. Hawker,Daniel Klinger +6 more
TL;DR: The development of crosslinked polyether particles as a reactive platform for the preparation of functional microgels that are responsive to different triggers but are characterized by the same size distribution, surface functionality, and crosslinking density is reported.
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Terbinafine hydrochloride nanovesicular gel: In vitro characterization, ex vivo permeation and clinical investigation.
TL;DR: In vivo animal study showed that the lowest fungal burden was produced with ELI4 chitosan gel, compared to 20% for market product (Lamisil® cream), and clinical studies showed cure rate of 86% within 7days treatment in case of limonene nanovesicular gel.
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Measuring Protein Binding to Individual Hydrogel Nanoparticles with Single-Nanoparticle Surface Plasmon Resonance Imaging Microscopy
TL;DR: The specific binding and uptake of protein molecules to individual hydrogel nanoparticles is measured with real-time single-nanoparticle surface plasmon resonance imaging (SPRI) microscopy, and the distribution of Δ%RNP values observed for individual nanoparticles can be used to learn more about the nature of the protein–nanoparticles interaction.
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Thieno[3,2-b]thiophene-DPP based near-infrared nanotheranostic agent for dual imaging-guided photothermal/photodynamic synergistic therapy
TL;DR: PDBr NPs can effectively impede the tumor growth without noticeable side effects in living mice through imaging-guided synergistic photothermal/photodynamic therapy in the clinic and could be a promising nanotheranostic agent for imaging- guided synergistic Photothermal and photodynamic therapy on the clinic.
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Preparation and biomedical application of injectable hydrogels
TL;DR: This review summarizes the current state of research in injectable hydrogels, highlights the synthesis of injectable Hydrogels and their applications in the biomedical field, and provides some insights into the future development.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.