Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
Citations
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Development of pH Sensitive Alginate/Gum Tragacanth Based Hydrogels for Oral Insulin Delivery
TL;DR: The hydrogels formulated from biodegradable, biocompatible, and nontoxic natural polymers were seen as promising devices for potential oral insulin delivery and the presence of CH revealed that ALG-GT gel formulation could be used as an oral insulin carrier at optimum concentrations.
Journal ArticleDOI
Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides.
Simone A. Costa,Joseph R. Simon,Miriam Amiram,Miriam Amiram,Lei Tang,Stefan Zauscher,Eric M. Brustad,Farren J. Isaacs,Ashutosh Chilkoti +8 more
TL;DR: This work represents a fundamental advance in the generation of crosslinked biomaterials, especially in the form of soft matter colloids, and is one of the first demonstrations of successful use of UAAs in generating a novel material.
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Photosensitive microgels containing azobenzene surfactants of different charges
Selina Schimka,Nino Lomadze,Maren Rabe,Alexey Kopyshev,Maren Lehmann,Regine von Klitzing,Artem M. Rumyantsev,Elena Yu. Kramarenko,Svetlana Santer +8 more
TL;DR: Utilization of polyamine azobenzene containing surfactants for the light triggered remote control of the microgel size opens up a possibility for applications of light responsive microgels as drug carriers in biology and medicine.
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Poly(lactic acid) based hydrogels: formation, characteristics and biomedical applications
TL;DR: The PLA based thermo-responsive hydrogels have effectively been used for wound healing, tissue engineering as well as drug control and release, and possible biomedical applications are given.
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Preparation and characterization of self-assemblied nanoparticles based on folic acid modified carboxymethyl chitosan
Yu-long Tan,Chenguang Liu +1 more
TL;DR: Cellular uptake of FCC nanoparticles was found to be higher than that of nanoparticles based on linoleic acid (LA) modified carboxymethyl chitosan because of the FA-receptor-mediated endocytosis, thereby providing higher cytotoxicity against Hela cells.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.