Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Bioinspired microstructures of chitosan hydrogel provide enhanced wear protection.
Jimmy Faivre,Guillaume Sudre,Alexandra Montembault,Stéphane Benayoun,Xavier Banquy,Xavier Banquy,Thierry Delair,Laurent David +7 more
TL;DR: The fabrication of physical chitosan hydrogels exhibiting a layered structure that favors diffusion of macromolecules within the hydrogel matrix up to a critical pressure, σc, and found that the SZ provided a higher wear resistance than the DZ which was severely damaged at a pressure equal to the elastic modulus of the gel.
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Antivenom Production against Bothrops jararaca and Bothrops erythromelas Snake Venoms Using Cross-Linked Chitosan Nanoparticles as an Immunoadjuvant
Karla Samara Rocha Soares,Fiamma Gláucia-Silva,Alessandra Daniele-Silva,Manoela Torres-Rêgo,Nathália Kelly de Araújo,Yamara A. S. Menezes,Igor Zumba Damasceno,Denise V. Tambourgi,Arnóbio Antônio da Silva-Júnior,Matheus F. Fernandes-Pedrosa +9 more
TL;DR: Evaluation of protein interactions with the CNPs revealed their ability to induce antibody levels equivalent to those of AH, even with smaller doses of antigen, and CNPs were less inflammatory due to their modified release of proteins.
Doxorubicin-loaded boron-rich polymer nanoparticles for orthotopically implanted liver tumor treatment
TL;DR: The in vivo behaviors of doxorubicin (DOX)-loaded dextran-poly(3-acrylamidophenylboronic acid) (Dextran-PAPBA) nanoparticles (NPs) were studied, revealing that the DOX-loaded NPs formulation had better antitumor effect than free DOX.
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Strong fish gelatin hydrogels double crosslinked by transglutaminase and carrageenan
TL;DR: In this paper , strong fish gelatin hydrogels were successfully prepared by double crosslinking gelatin with transglutaminase (TGase) and κ-carrageenan, and the mechanical properties and thermal stability of the double crosslinked gelatin was significantly improved.
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Preparation and characterization of magnetic nanohydrogel based on chitosan for 5-fluorouracil drug delivery and kinetic study
TL;DR: In this paper , chitosan-polyacrylic acid encapsulated Fe3O4 magnetic nanogelic core-shell was synthesized in the presence of glutaraldehyde used for loaded anticancer 5-fluorouracil (5-FU) drug.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
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Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.