Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
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TLDR
Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2008-12-14. It has received 1704 citations till now. The article focuses on the topics: Nanogel & Drug carrier.read more
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Nano-hydrogels of methoxy polyethylene glycol-grafted branched polyethyleneimine via biodegradable cross-linking of Zn 2+ -ionomer micelle template
TL;DR: This functional nanocarrier is expected to exhibit some key features such as active encapsulation of negatively charged hydrophilic agents in the swollen core of polyamine network and a hydrophobic mPEG shell which provides an increased solubility and passive targeting of active pharmaceutical agents to impaired tissues.
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Recent progress in PNIPAM-based multi-responsive actuators: A mini-review
TL;DR: In this paper, a review comprehensively introduces the construction methods of the PNIPAM-based hydrogel actuators, based on the types of environmental response, the designs and applications of the environmental stimuli-responsive hydrogels actuators based on poly(N-isopropylacrylamide) are discussed.
Journal ArticleDOI
Recent progress in PNIPAM-based multi-responsive actuators: A mini-review
TL;DR: In this paper , a review comprehensively introduces the construction methods of the PNIPAM-based hydrogel actuators, based on the types of environmental response, the designs and applications of the environmental stimuli-responsive hydrogels actuators based on poly(N-isopropylacrylamide) are discussed.
Journal ArticleDOI
Antitumor Effect of Lonidamine-Polypeptide-Peptide Nanoparticles in Breast Cancer Models.
Ifat Cohen-Erez,Carol Issacson,Yael Lavi,Ruthy Shaco-Levy,Jammi Milam,Brenda Laster,Levi A. Gheber,Hanna Rapaport +7 more
TL;DR: NP size, as well as their ability to target the proximity of the mitochondria of breast cancer cells were both maintained in this new formulation, C-LND-mPoP-NPs, which exhibited 40% better cytotoxicity and led to tumor growth inhibition with no adverse side effects, upon intravenous administration in a xenograft breast cancer murine model.
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One pot synthesis and characterization of Fe3O4 Nanorod-PNIPA Nanogel Composite for protein adsorption
TL;DR: Fe3O4 Nanorod-PNIPA Nanogel Composite nanomaterial is appeared as a fast catalyst for lysozyme like protein immobilization.
References
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Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
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Environment-sensitive hydrogels for drug delivery
Yong Qiu,Kinam Park +1 more
TL;DR: Development of environmentally sensitive hydrogels with a wide array of desirable properties can be made is a formidable challenge, however, if the achievements of the past can be extrapolated into the future, it is highly likely that responsive hydrogelWith such properties can been made.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.