Francesca Marino-Merlo

TL;DR: Observations reported in this mini-review suggest that a better understanding of molecular dysfunctions in inflammatory and cell death/autophagy pathways, both in the brain and peripheral blood, could provide useful targets for future investigation on drug-discovery and biomarker identification in PD.

TL;DR: It is established that HVEM is involved in NF‐κB activation by HSV‐1 gD, and this activation is related to herpesvirus entry mediator activity.

TL;DR: A comprehensive picture of general aspects of inflammation and apoptosis in MS is given, with special emphasis on the until now not well highlighted possible links between phenomena relevant to these aspects occurring in either the periphery or in the CNS during MS.

TL;DR: Results suggest that signaling triggered by binding of gD to HV EM could represent an additional mechanism of evasion from premature apoptotic death exerted by HSV-1-gD in HVEM-expressing cells, disclosing new opportunities of cell death manipulation by using gD preparations.

TL;DR: The present work has presented a novel single-cell analysis pipeline to identify specific biomarkers of HIV permissiveness and the importance of the tax-inducible actin-bundling protein fascin for transmission of human T cell leukemia virus Type 1 (HTLV-1).