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Open AccessJournal ArticleDOI

Metadata matters: access to image data in the real world

TLDR
An open standard format for multidimensional microscopy image data is described and it is called on the community to use open image data standards and to insist that all imaging platforms support these file formats.
Abstract
Data sharing is important in the biological sciences to prevent duplication of effort, to promote scientific integrity, and to facilitate and disseminate scientific discovery. Sharing requires centralized repositories, and submission to and utility of these resources require common data formats. This is particularly challenging for multidimensional microscopy image data, which are acquired from a variety of platforms with a myriad of proprietary file formats (PFFs). In this paper, we describe an open standard format that we have developed for microscopy image data. We call on the community to use open image data standards and to insist that all imaging platforms support these file formats. This will build the foundation for an open image data repository.

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Book ChapterDOI

Open data and software for microscopy image analysis

TL;DR: This chapter presents a few representative open-source datasets and software for microscopy image analysis to enable the reader to jump start their investigation by having readily accessible data and analysis software, so they can bring about further progress in this important area.
Journal ArticleDOI

Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds.

TL;DR: In this article , the authors used two different polymeric particles for delivery of compounds, i.e., poly(lactic-co-glycolic acid)50:50 and poly(methyl methacrylate-stat-methacrylic acid)90:10 yielding particles with hydrodynamic diameters ranging from 100 to 300 nm.
Journal ArticleDOI

Droplet-based microfluidic platform for viscosity measurement over extended concentration range.

Nicolas Bremond, +1 more
- 18 Apr 2023 - 
TL;DR: In this paper , a microfluidics and microrheology-based approach is proposed to study the viscosity of concentrated protein solutions. But the authors focus on a specific micro system to study viscosities of aqueous solutions at high concentrations.
References
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Journal ArticleDOI

Genome-wide atlas of gene expression in the adult mouse brain

Ed S. Lein, +109 more
- 11 Jan 2007 - 
TL;DR: An anatomically comprehensive digital atlas containing the expression patterns of ∼20,000 genes in the adult mouse brain is described, providing an open, primary data resource for a wide variety of further studies concerning brain organization and function.
Journal ArticleDOI

Global Analysis of mRNA Localization Reveals a Prominent Role in Organizing Cellular Architecture and Function

TL;DR: A high-resolution fluorescent in situ hybridization procedure was developed and employed to comprehensively evaluate mRNA localization dynamics during early Drosophila embryogenesis, indicating major roles for mRNA localization in nucleating localized cellular machineries.
Journal ArticleDOI

The Zebrafish Information Network: the zebrafish model organism database

TL;DR: The Zebrafish Information Network (ZFIN) provides an integrated representation of mutants, genes, genetic markers, mapping panels, publications and community resources such as meeting announcements and contact information.
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The FAIR Guiding Principles for scientific data management and stewardship