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Open AccessJournal ArticleDOI

Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation

Chiu Wing Lam, +3 more
- 26 Sep 2003 - 
- Vol. 77, Iss: 1, pp 126-134
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.
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This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.

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Tendons: Engineering of Functional Tissues

TL;DR: The structural composition of the native tendon is discussed, approaches in engineering tendon substitutes are summarized and it is of paramount importance to understand how the tissue forms and behaves in vivo.
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Carbon nanotubes for in vivo cancer nanotechnology

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In vitro toxicity of nanosized copper particles in PC12 cells induced by oxidative stress

TL;DR: Investigation of the cytotoxicity induced by nanosized copper particles (nano-Cu) showed that the increasing of oxidative stress was a key mechanism in PC12 apoptosis induced by nano-Cu, and both excessive intracellular ROS and decreased SOD contributed to nano- Cu-induced cytot toxicity.
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Carbon Nanotubes and Chronic Granulomatous Disease

TL;DR: Evidence for similarities in the pathophysiology of carbon nanotube-induced pulmonary disease in experimental animals with that of the human granulomatous disease, sarcoidosis is discussed.

FORUM SERIES Research Strategies for Safety Evaluation of Nanomaterials, Part IV: Risk Assessment of Nanoparticles

TL;DR: A review of recent findings in exposure and toxicity of nanoparticles and their application for assessing human health risks is presented in this paper, along with risk assessments that will be used to regulate the use of nanomaterials in consumer products.
References
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Journal ArticleDOI

Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.

TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI

Large-scale purification of single-wall carbon nanotubes: process, product, and characterization

TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal ArticleDOI

Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material

TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI

Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study

TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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