Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Inorganic nanomaterials for tumor angiogenesis imaging
Zhuang Liu,Rui Peng +1 more
TL;DR: Although the application of inorganic nanomaterials in clinical imaging and diagnosis is still facing many challenges, the unique properties and functions of these novel nanoprobes make them very promising agents in angiogenesis imaging and could bring great opportunities to this fast-growing field.
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Biocompatible and Stable GO-Coated Fe3O4 Nanocomposite: A Robust Drug Delivery Carrier for Simultaneous Tumor MR Imaging and Targeted Therapy
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TL;DR: Cell viability and in vitro biocompatibility studies of the FA-Fe3O4@nGO-DOX NPs revealed their selective uptake by MGC-803 cells and in vivo antitumor activity and histological analysis confirmed the selective anticancer activity of the modified NPs.
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Colony Forming Efficiency and microscopy analysis of multi-wall carbon nanotubes cell interaction.
Jessica Ponti,Renato Colognato,Hubert Rauscher,Sabrina Gioria,Francesca Broggi,Fabio Franchini,Cesar Pascual,Guido Giudetti,François Rossi +8 more
TL;DR: In this article, a complete physicochemical characterization of multi-wall carbon nanotubes (mwCNTs) in order to assess their potential toxicological effects in in vitro cell models using Colony Forming Efficiency (CFE) assay is presented.
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Sustainable governance of emerging technologies—Critical constellations in the agent network of nanotechnology
TL;DR: In this paper, a transdisciplinary study on the agent network of nanotechnology in Switzerland reveals, among others, missing key agents, non-fulfillment of required functions, nonavailability of required knowledge, and deviations between self and cross-perception.
Journal ArticleDOI
Biodistribution of 99mTc-C60(OH)x in Sprague–Dawley rats after intratracheal instillation
Jing-Ying Xu,Qingnuan Li,Jungang Li,Tiecheng Ran,Sheng-wei Wu,Wei-Min Song,Shao-Liang Chen,Wenxin Li +7 more
TL;DR: The results provide guidance for further study of the respiratory toxicity of carbon nanornaterials and the dimensions and size distribution, as well as in vivo aggregation of 99mTc-C60(OH)(x),, may affect the capability and kinetic process of penetrating the alveolar-capillary barrier.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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