Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Novel applications of nanotechnology in medicine.
TL;DR: The various platforms of nanotechnology being used in different aspects of medicine like diagnostics and therapeutics and the potential toxicities of the nanoparticles are described in addition to hypothetical designs such as respirocytes and microbivores are described.
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Nanoparticles and the blood coagulation system. Part II: safety concerns.
TL;DR: The relationship between the physicochemical properties of nanoparticles that determine their negative effects on the blood coagulation system will be discussed in order to understand how manipulation of these properties can help to overcome unwanted side effects.
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Relative risk analysis of several manufactured nanomaterials: an insurance industry context
TL;DR: Results from this analysis determined that relative environmental risk from manufacturing each of these five materials was comparatively low in relation to other common industrial manufacturing processes.
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On the Toxicity of Therapeutically Used Nanoparticles: An Overview
Afaf El-Ansary,Sooad Al-Daihan +1 more
TL;DR: The objective of this review was to trace the cellular response to nanosized particle exposure and highlight the need for caution during the use and disposal of such manufactured nanomaterials to prevent unintended environmental impacts.
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Single-Walled Carbon Nanotubes Induces Oxidative Stress in Rat Lung Epithelial Cells
Chidananda S. Sharma,Shubhashish Sarkar,Adaikkappan Periyakaruppan,Johnny Barr,Kimberly Wise,Renard L. Thomas,Bobby L. Wilson,Govindarajan T. Ramesh +7 more
TL;DR: The results prove that SWCNT induces oxidative stress in LE cells and shows loss of antioxidants, and that mitochondria is not involved inSWCNT induced ROS production.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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