Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities.
Kelly Fraser,Kelly Fraser,Vamsi Kodali,Vamsi Kodali,Naveena Yanamala,Naveena Yanamala,M. Eileen Birch,Lorenzo Cena,Gary S. Casuccio,KL Bunker,Traci L. Lersch,Douglas E. Evans,Aleksandr B. Stefaniak,Mary Ann Hammer,Michael L. Kashon,Theresa Boots,Tracy Eye,John Hubczak,John Hubczak,Sherri Friend,Matthew M. Dahm,Mary K. Schubauer-Berigan,Mary K. Schubauer-Berigan,Katelyn J. Siegrist,David T. Lowry,Alison K. Bauer,Linda M. Sargent,Aaron Erdely,Aaron Erdely +28 more
TL;DR: Distributions of physical dimensions provided more consistent grouping of CNT/F with respect to toxicity outcomes compared to means only, and many of the traditional physicochemical characteristics including surface area, density, impurities, and dustiness did not cluster with the toxicity outcomes.
Journal ArticleDOI
A new strategy to probe the genotoxicity of silver nanoparticles combined with cetylpyridine bromide.
TL;DR: The environmental genotoxic behavior of silver nanoparticles (nanoAg) combined with the detergent cetylpyridine bromide (CPB) was examined in vitro and it was shown that nanoAg shows obvious genotoxicity after combined with CPB.
Journal ArticleDOI
Cockle Shell-Derived Calcium Carbonate (Aragonite) Nanoparticles: A Dynamite to Nanomedicine
Maryam Muhammad Mailafiya,Kabeer Abubakar,Abubakar Danmaigoro,Samaila Musa Chiroma,Ezamin Abdul Rahim,Mohamad Aris Mohd Moklas,Zuki Abu Bakar Zakaria +6 more
TL;DR: A review on a few different types of nanoparticles with emphasis on the versatile most recent advancements and achievements on the synthesis and developments of CSCaCO3NP aragonite with its applications as a nanocarrier for drug delivery in nanomedicine is presented in this paper.
Journal ArticleDOI
Metabolic impact induced by total, water soluble and insoluble components of PM2.5 acute exposure in mice.
Yannan Zhang,Yanbo Li,Zhixiong Shi,Jing Wu,Xiaozhe Yang,Lin Feng,Lihua Ren,Junchao Duan,Zhiwei Sun +8 more
TL;DR: Evaluating the toxicity of different components of PM2.5 at molecular level via metabolomics approach suggested that acute exposure to the Total-PM 2.5, WS-PM2.
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Molecular Dynamics Studies for Optimization of Noncovalent Loading of Vinblastine on Single-Walled Carbon Nanotube
TL;DR: In this paper, the interaction between vinblastine and carbon nanotubes was investigated under different conditions, such as terminal esterification and functionalization of the carbon-nanotubes.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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