Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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New risk or old risk, high risk or no risk? How scientists' standpoints shape their nanotechnology risk frames
TL;DR: In this article, the authors compared the risk frames of scientists who are developing new nanotechnologies (upstream scientists) with those of those who might later study the health effects of these technologies (downstream scientists).
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Macrophage polarization and activation at the interface of multi-walled carbon nanotube-induced pulmonary inflammation and fibrosis.
TL;DR: Molecular analysis revealed MWCNTs boosted specific STAT and IRF signaling pathways to regulate M1 and M2 polarization in the lungs through the polarization and activation of macrophages during M WCNT-induced lung pathologic response.
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ACS-22, a protein homologous to mammalian fatty acid transport protein 4, is essential for the control of the toxicity and translocation of multi-walled carbon nanotubes in Caenorhabditis elegans
TL;DR: Loss-of-function mutation of the acs-22 gene strengthened MWCNT toxicity to the functions of both primary targeted organs such as intestine and secondary targeted organssuch as neurons and reproductive organs; however, overexpression of theacs- 22 gene reduced the toxicity of M WCNTs to the function of bothPrimary and secondary targeting organs.
Journal ArticleDOI
A highly efficient and versatile carbon nanotube/ceramic composite filter
TL;DR: Carbon nanotubes were grown in the open pores of a commercial porous ceramic matrix consisting of mainly Al 2 O 3 and SiO 2 with an average pore size of 300 and 500μm, using a pre-formed nickel catalyst inside the pores and a camphor solution precursor at 780°C.
Journal ArticleDOI
Potential occupational exposure to manufactured nanoparticles in Italy
TL;DR: In this article, the authors focus on the potential occurrence of nanoparticles in some economic sectors and propose an estimate of the number of workers involved, which is a basic step in the general process of risk analysis in order to establish the size and impact of the hazard.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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