Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Journal ArticleDOI
Electrically conductive nanomaterials for cardiac tissue engineering.
Khadijeh Ashtari,Hojjatollah Nazari,Hyojin Ko,Peyton Tebon,Masoud Akhshik,Mohsen Akbari,Sanaz Naghavi Alhosseini,Masoud Mozafari,Bita Mehravi,Masoud Soleimani,Reza Ardehali,Majid Ebrahimi Warkiani,Samad Ahadian,Ali Khademhosseini +13 more
TL;DR: The recent application of electrically conductive nanomaterials to the development of scaffolds for cardiac tissue engineering is highlighted and the effects of these nanommaterials on cardiac cell behavior such as proliferation and migration, as well as cardiomyogenic differentiation in stem cells are summarized.
Journal ArticleDOI
Current investigations into carbon nanotubes for biomedical application
TL;DR: In this review, five parts are stated, which might indicate that CNTs, with a range of unique properties, appear suited as a biomaterial and may become a useful tool for tissue engineering.
Journal ArticleDOI
Biological cellular response to carbon nanoparticle toxicity
Barbara J. Panessa-Warren,John B. Warren,Stanislaus S. Wong,Stanislaus S. Wong,James A. Misewich +4 more
TL;DR: This paper reviews the current research on the reactivity and interactions of carbon nanoparticle interactions with biological cells in vivo and in vitro, with ultrastructural images demonstrating evidence of human cell cytotoxicity to carbon nanoparticles characteristic of lipid membrane peroxidation, gene down regulation of adhesive proteins, and increased cell death.
Journal ArticleDOI
Effect of particle dimension on biocompatibility of carbon nanomaterials
Christin M. Grabinski,Christin M. Grabinski,Saber M. Hussain,Khalid Lafdi,Laura K. Braydich-Stolle,John J. Schlager +5 more
TL;DR: In this article, the cellular effects of carbon-based materials with diameters ranging from micro-to nano-dimension were investigated using mouse keratinocytes (HEL-30).
Journal ArticleDOI
Characterization and Evaluation of Nanoparticle Release during the Synthesis of Single-Walled and Multiwalled Carbon Nanotubes by Chemical Vapor Deposition
Su-Jung (Candace) Tsai,Mario Hofmann,Marilyn F. Hallock,Earl Ada,Jing Kong,Michael J. Ellenbecker +5 more
TL;DR: Different operating conditions of multi-walled carbon nanotubes (MWCNT) production were studied to evaluate their effects on the number and morphology of aerosol particles, and the number of particles released.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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