Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Novel neural interface for implant electrodes: improving electroactivity of polypyrrole through MWNT incorporation.
TL;DR: In this paper, multi-walled carbon nanotubes (MWNTs) are incorporated into conductive polymers to produce superior materials for neural interfaces with high interfacial areas, conductivity and electrochemical stability.
Journal ArticleDOI
Cardiac autonomic regulation after lung exposure to carbon nanotubes
Jacopo M. Legramante,Federica Valentini,Andrea Magrini,Giuseppe Palleschi,Sacco S,Ivo Iavicoli,Marco Pallante,Danila Moscone,Alberto Galante,Enrico Bergamaschi,Antonio Bergamaschi,Antonio Pietroiusti +11 more
TL;DR: It is suggested that engineered nanoparticles, such as single-walled carbon nanotubes (SWCNTs), may alter the arterial baroreflex function, thus affecting the autonomic cardiovascular control regulation.
Journal ArticleDOI
Induction of apoptosis in rat lung epithelial cells by multiwalled carbon nanotubes.
Prabakaran Ravichandran,Adaikkappan Periyakaruppan,Bindu Sadanandan,Vani Ramesh,Joseph C. Hall,Olufisayo Jejelowo,Govindarajan T. Ramesh +6 more
TL;DR: Investigating the adverse effects of multiwalled CNTs in rat lung epithelial (LE) cells reveals that MWCNTs induced oxidative stress and stimulated apoptosis pathway through caspase activation in rat LE cell lines.
Journal ArticleDOI
Amphiphilic helical peptide enhances the uptake of single-walled carbon nanotubes by living cells
Shook Fong Chin,Ray H. Baughman,Alan B. Dalton,Gregg R. Dieckmann,Rockford K. Draper,Carole Mikoryak,Inga H. Musselman,Vasiliki Z. Poenitzsch,Hui Xie,Paul Pantano +9 more
TL;DR: The enhanced uptake by HeLa cells of single-walled CNTs coated with a designed peptide termed nano-1 is reported, showing that the purified CNT dispersions are taken up by He La cells in a time- and temperature-dependent fashion and do not affect the HeLa cell growth rate.
Journal ArticleDOI
The effects of carbon nanotubes on the proliferation and differentiation of primary osteoblasts
TL;DR: In this article, the effects of single-walled carbon nanotubes (SWNTs), double-weled carbon nanotsubes (DWNTs) and multiwalled carbon Nanotube (MWNT) on the proliferation, differentiation, adipocytic transdifferentiation and mineralization of primary osteoblasts were investigated.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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