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Open AccessJournal ArticleDOI

Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation

Chiu Wing Lam, +3 more
- 26 Sep 2003 - 
- Vol. 77, Iss: 1, pp 126-134
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.
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This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.

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Citations
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Nanoparticles as a Potential Cause of Pleural and Interstitial Lung Disease

TL;DR: The potential risks of engineered nanoparticles and nanotechnology on the respiratory system are overviewed and recent findings related to pulmonary and systemic effects of inhaled nanoparticles are highlighted.

Nanotechnology White Paper

Ord, +2 more
Journal ArticleDOI

Carbon nanotube (CNT) gas sensors for emissions from fossil fuel burning

TL;DR: In this paper, a review of carbon nanotubes (CNTs) chemiresistive gas sensing mechanisms is presented, which make them suitable for the development of next generation sensor technology.
Journal ArticleDOI

Nanoparticles, Lung Injury, and the Role of Oxidant Stress

TL;DR: Current research on incidental and engineered nanoparticles in terms of their health effects on lungs and the mechanisms by which oxidative stress via physicochemical characteristics influences toxicity or biocompatibility are examined.
Journal ArticleDOI

Nanomedicines as Cancer Therapeutics: Current Status

TL;DR: This review highlights nanopharmaceuticals that have been investigated in oncology for various applications (diagnosis, therapeutic delivery and theranostics), and discusses the effects of nano-sized materials on tissues/organ functions, the possibility of overcoming multi-drug resistance by using nanomedicines and their current clinical status.
References
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Journal ArticleDOI

Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.

TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI

Large-scale purification of single-wall carbon nanotubes: process, product, and characterization

TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal ArticleDOI

Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material

TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI

Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study

TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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