Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
Citations
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Cytotoxicity of water-soluble fullerene in vascular endothelial cells.
Hideyuki Yamawaki,Naoharu Iwai +1 more
TL;DR: Although exposure to nanomaterials appears to represent a risk for cardiovascular disorders, further in vivo validations are necessary, and only maximal doses of fullerenes caused cytotoxic injury and/or death and inhibited cell growth.
Journal ArticleDOI
Applications of nanomaterials inside cells
Jinhao Gao,Bing Xu,Bing Xu +2 more
TL;DR: The applications of various types of nanomaterials inside cells ranging from cell imaging and cell tracking to cancer treatment are described.
Journal ArticleDOI
Critical Review on the Toxicity of Some Widely Used Engineered Nanoparticles
TL;DR: In this paper, the authors have shown that nanoparticles have shown major toxic effects on fauna, flora, and human beings, such as inflammation, cytotoxicity, tissue ulceration, and reduction of cell viability.
Journal ArticleDOI
Review of toxicity studies of carbon nanotubes.
TL;DR: This work reviewed studies on pulmonary, reproductive, and developmental toxicity caused by carbon nanotubes and analyzed how CNT exposure affects the several processes of pulmonary toxicity, including inflammation, injury, fibrosis, and pulmonary tumors.
Journal ArticleDOI
Toxicity of single-walled carbon nanohorns
TL;DR: The present results strongly suggest that as-grown SWNHs have low acute toxicities and negative mutagenic and clastogenic potentials suggest thatSWNHs are not carcinogenic.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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