Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
Citations
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A critical evaluation of material safety data sheets (MSDSs) for engineered nanomaterials.
TL;DR: The majority (67%) of the MSDSs obtained in 2010-2011 still provided insufficient data for communicating the potential hazards of engineered nanomaterials.
Journal ArticleDOI
Respiratory toxicities of nanomaterials -- a focus on carbon nanotubes.
TL;DR: This review will highlight the advancement in the actual knowledge on lung toxicities of CNT, and try to better understand the underlying biological mechanisms, as well as the importance of physico-chemical determinants directly related to CNT characteristics.
Book
Nanotechnology: A Policy Primer
TL;DR: The U.S. Congress has demonstrated continuing support for nanotechnology and has directed its attention primarily to three topics that may affect the realization of this hoped for potential: federal research and development (RDU), environmental, health, and safety (EHS) concerns.
Journal ArticleDOI
In vitro toxicity of carbon nanotubes, nano-graphite and carbon black, similar impacts of acid functionalization.
Agathe Figarol,Jérémie Pourchez,Delphine Boudard,Valérie Forest,Céline Akono,Jean Marc Christian Tulliani,J.P. Lecompte,Michèle Cottier,Didier Bernache-Assollant,Philippe Grosseau +9 more
TL;DR: At equivalent dose expressed in surface and equivalent surface chemistry, the toxicological responses from murine macrophages to NG were higher than for CNT and CB, which seemed to correspond to the hypothesis of a platelet and fiber paradigm.
Journal ArticleDOI
Toxicity of Carbon Nanotubes as Anti-Tumor Drug Carriers.
Hong-Li Yan,Zhifeng Xue,Jia-Rong Xie,Yixiao Dong,Zhe Ma,Xinru Sun,Dereje Kebebe Borga,Dereje Kebebe Borga,Zhidong Liu,Jiawei Li +9 more
TL;DR: This review has focused on the potential toxic effects of carbon nanotubes utilized as anti-tumor drug carriers, the main modes by which CNTs enter target sites, the toxicity expressive types and the factors affecting toxicity are discussed.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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