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Open AccessJournal ArticleDOI

Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation

Chiu Wing Lam, +3 more
- 26 Sep 2003 - 
- Vol. 77, Iss: 1, pp 126-134
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.
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This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.

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Citations
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Journal ArticleDOI

In vivo activation of a T helper 2-driven innate immune response in lung fibrosis induced by multi-walled carbon nanotubes.

TL;DR: This study uncovers activation of a Th2-driven immune/inflammatory response during pulmonary fibrosis development induced by MWCNT, providing novel insights into the molecular events that control the transition from an acute inflammatory response to chronic fibrosis through Th2 functions in CNT-exposed lungs.
Journal ArticleDOI

Synthesis, characterization and cytotoxicity of phosphoryl choline-grafted water-soluble carbon nanotubes

TL;DR: In this paper, carbon nanotubes (CNTs) were rendered water-soluble by grafting on phosphoryl choline (PC), and the modified CNTs were characterized utilizing Fourier transform infrared spectra, X-ray photoelectron spectra and dynamic laser light-scattering.
Journal ArticleDOI

Highly sensitive and durable wearable strain sensors from a core-sheath nanocomposite yarn

TL;DR: In this paper, a core-sheath nanocomposite yarn (CSCY) based wearable sensor with high sensitivity and superior durability is presented. But, it is still challenging to fabricate wearable strain sensors with sensitivity and durability.
Journal Article

Carbon nanotubes induce granulomas but not mesotheliomas.

TL;DR: The present studies with rats indicate that early granuloma formation does not lead to the development of mesotheliomas during chronic exposure of peritoneal Mesothelium to either single- or multi-walled carbon nanotubes of varied size.
Journal ArticleDOI

Biocatalytic Synthesis Pathways, Transformation, and Toxicity of Nanoparticles in the Environment

TL;DR: A comprehensive review on the biocatalytic production pathways, transformations, and toxicity to human and other organisms of important NPs, as well as their physicochemical alterations, is provided.
References
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Journal ArticleDOI

Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.

TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI

Large-scale purification of single-wall carbon nanotubes: process, product, and characterization

TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal ArticleDOI

Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material

TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI

Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study

TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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