Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
Reads0
Chats0
TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
Citations
More filters
Journal ArticleDOI
Persistent DNA damage measured by comet assay of Sprague Dawley rat lung cells after five days of inhalation exposure and 1 month post-exposure to dispersed multi-wall carbon nanotubes (MWCNTs) generated by new MWCNT aerosol generation system.
Jin Sik Kim,Jae Huyck Sung,Kyung Seuk Song,Ji Hyun Lee,Sun Man Kim,Gun Ho Lee,Kang Ho Ahn,Jong Seong Lee,Jae Hoon Shin,Jung Duck Park,Il Je Yu +10 more
TL;DR: The MWCNTs caused a statistically significant increase in lung DNA damage at high concentration when compared with the negative control group on day 0 and 1 month postexposure, and this study investigated the inhalation toxicity potential of multiwall CNTs.
Journal ArticleDOI
Stabilizing single-walled carbon nanotubes by removal of residual metal catalysts
TL;DR: In this paper, the authors demonstrate that the removal of residual metals can dramatically enhance the stability of single wall carbon nanotubes (SWCNTs) and show that the activation energy for oxidation increased by 50% and frequency factor by nearly four orders of magnitude.
Journal ArticleDOI
Engineered nanoparticles: safer substitutes for toxic materials, or a new hazard?
Michael J. Ellenbecker,S. Tsai +1 more
TL;DR: In this article, the potential adverse environmental health and safety aspects of the new nanomaterials are discussed. But, although a few examples from the literature are encouraging, great care must be taken to perform complete alternatives assessment evaluations of any new nanotechnology-enabled product before its adoption.
Journal ArticleDOI
Toxicity of single-walled carbon nanotube: How we were wrong?
TL;DR: In this paper, the authors argue that the contradictory data on the toxic effects of single-walled carbon nanotubes (SWCNT) make us believe that it is appropriate and necessary.
Journal ArticleDOI
Recent Advances of Nanoremediation Technologies for Soil and Groundwater Remediation: A Review
Motasem Y. D. Alazaiza,Ahmed Albahnasawi,Gomaa A. M. Ali,Mohammed J.K. Bashir,Nadim K. Copty,Salem S. Abu Amr,Mohammed F.M. Abushammala,Tahra Al Maskari +7 more
TL;DR: In this paper, a review of the application of nanomaterials for environmental cleanup, such as soil and groundwater remediation, is presented and discussed, and the potential environmental risks of the Nanomaterial application in soil remediation are highlighted.
References
More filters
Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
Related Papers (5)
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice
Anna A. Shvedova,Elena R. Kisin,Robert R. Mercer,Ashley R. Murray,Victor J. Johnson,Alla I. Potapovich,Yulia Y. Tyurina,Olga Gorelik,Sevaram Arepalli,Diane Schwegler-Berry,Ann F. Hubbs,James M. Antonini,Douglas E. Evans,Bon Ki Ku,Dawn Ramsey,Andrew D. Maynard,Valerian E. Kagan,Vincent Castranova,Vincent Castranova,Paul A. Baron +19 more