Pulmonary Toxicity of Single-Wall Carbon Nanotubes in Mice 7 and 90 Days After Intratracheal Instillation
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TLDR
Results show that, for the test conditions described here and on an equal-weight basis, if carbon nanotubes reach the lungs, they are much more toxic than carbon black and can be more Toxic than quartz, which is considered a serious occupational health hazard in chronic inhalation exposures.About:
This article is published in Toxicological Sciences.The article was published on 2003-09-26 and is currently open access. It has received 1954 citations till now. The article focuses on the topics: Carbon nanotubes in medicine & Carbon nanotube.read more
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Journal ArticleDOI
Considerations for Safe Innovation: The Case of Graphene.
Margriet V. D. Z. Park,Eric A.J. Bleeker,Walter Brand,Flemming R. Cassee,Merel van Elk,Ilse Gosens,Wim H. de Jong,Johannes A.J. Meesters,Willie J.G.M. Peijnenburg,Joris T.K. Quik,Rob J. Vandebriel,Adriënne J.A.M. Sips +11 more
TL;DR: The possibilities of considering safety aspects during various stages of the innovation process of graphene, outlining what information is already available for assessing potential hazard, exposure, and risks are investigated.
Journal ArticleDOI
Evaluation of cell viability, DNA damage, and cell death in normal human dermal fibroblast cells induced by functionalized multiwalled carbon nanotube.
TL;DR: It was found to be toxic and induced massive loss of cell viability through DNA damage and programmed cell death of all doses compared to control and demonstrated that carbon nanotubes indeed can be very toxic at sufficiently high concentrations from environmental and occupational exposure.
Journal ArticleDOI
The splenic toxicity of water soluble multi-walled carbon nanotubes in mice
Xiaoyong Deng,Fei Wu,Zhen Liu,Man Luo,Ling Li,Qingshun Ni,Zheng Jiao,Minghong Wu,Yuanfang Liu,Yuanfang Liu +9 more
TL;DR: In this article, water soluble multi-walled carbon nanotubes (S-MWCNTs) were used as a model to investigate the possible toxicity of CNTs to mouse spleen.
Journal ArticleDOI
Nanoparticles for radiooncology: Mission, vision, challenges
Leoni A. Kunz-Schughart,Anna Dubrovska,Claudia Peitzsch,Alexander Ewe,Achim Aigner,Samuel Schellenburg,Michael H. Muders,Silke Hampel,Giuseppe Cirillo,Francesca Iemma,Rainer Tietze,Christoph Alexiou,Holger Stephan,Kristof Zarschler,Orazio Vittorio,Maria Kavallaris,Wolfgang J. Parak,Lutz Mädler,Suman Pokhrel +18 more
TL;DR: The radio- and tumor-biological rationales for combining nanostructures with radiotherapy, tumor-site targeting strategies and mechanisms of cellular uptake, and biological response hypotheses for new nanomaterials of interest are illustrated.
Journal ArticleDOI
Low-dimensional carbon based sensors and sensing network for wearable health and environmental monitoring
TL;DR: An in-depth overview and review of sensors and sensing networks for strain, pressure, surface bio-potential, gas and temperature, which are made from low-dimensional carbon nano-materials and their composites are presented.
References
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Journal ArticleDOI
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats.
TL;DR: Results from the lung histopathology component of the study indicated that pulmonary exposures to quartz particles produced dose-dependent inflammatory responses, concomitant with foamy alveolar macrophage accumulation and lung tissue thickening at the sites of normal particle deposition.
Journal ArticleDOI
Large-scale purification of single-wall carbon nanotubes: process, product, and characterization
Andrew G. Rinzler,Jie Liu,Hongjie Dai,Pavel Nikolaev,Chad B. Huffman,Fernando J. Rodríguez-Macías,Peter J. Boul,A.H. Lu,Dieter Heymann,Daniel T. Colbert,R. S. Lee,John E. Fischer,Apparao M. Rao,P. C. Eklund,Richard E. Smalley +14 more
TL;DR: A readily scalable purification process capable of handling single-wall carbon nanotube (SWNT) material in large batches, which should greatly facilitate investigation of material properties intrinsic to the nanotubes.
Journal Article
Deposition and retention models for internal dosimetry of the human respiratory tract. Task group on lung dynamics.
Journal ArticleDOI
Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material
Andrew D. Maynard,Paul A. Baron,Michael Foley,Anna A. Shvedova,Elena R. Kisin,Vincent Castranova +5 more
TL;DR: Although laboratory studies indicated that with sufficient agitation, unrefined SWCNT material can release fine particles into the air, concentrations generated while handling material in the field were very low, and estimates of the airborne concen-tration of nanotube material generated during handling suggest that concentrations were lower than 53μg/m3 in all cases.
Journal ArticleDOI
Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: A parametric study
TL;DR: The HiPco process has been used to produce high-purity carbon single-walled nanotubes (SWNTs) using a gas-phase chemical-vapor-deposition process as mentioned in this paper.
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