Open AccessJournal Article
R: A language and environment for statistical computing.
Reads0
Chats0
TLDR
Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.Abstract:
Copyright (©) 1999–2012 R Foundation for Statistical Computing. Permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and this permission notice are preserved on all copies. Permission is granted to copy and distribute modified versions of this manual under the conditions for verbatim copying, provided that the entire resulting derived work is distributed under the terms of a permission notice identical to this one. Permission is granted to copy and distribute translations of this manual into another language, under the above conditions for modified versions, except that this permission notice may be stated in a translation approved by the R Core Team.read more
Citations
More filters
Journal ArticleDOI
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study
Philip C Haycock,Stephen Burgess,Aayah Nounu,Jie Zheng,G N Okoli,Jack Bowden,Kaitlin H Wade,Nicholas J. Timpson,David M. Evans,Peter Willeit,Abraham Aviv,Tom R. Gaunt,Gibran Hemani,Massimo Mangino,Hayley P Ellis,Kathreena M Kurian,Karen A. Pooley,Rosalind A. Eeles,Jeffrey E. Lee,Shenying Fang,Wei V. Chen,Matthew Law,Lisa Bowdler,Mark M. Iles,Qiong Yang,Bradford B. Worrall,Hugh S. Markus,Rayjean J. Hung,Christopher I. Amos,Amanda B. Spurdle,Deborah J. Thompson,Tracy A. O'Mara,Brian M. Wolpin,Laufey T. Amundadottir,Rachael Z. Stolzenberg-Solomon,Antonia Trichopoulou,N. Charlotte Onland-Moret,Eiliv Lund,Eric J. Duell,Federico Canzian,Gianluca Severi,Kim Overvad,Marc J. Gunter,Rosario Tumino,Ulrika Svenson,Andre M. van Rij,Annette F. Baas,Matthew J. Bown,Nilesh J. Samani,Femke N G van t'Hof,Gerard Tromp,Gregory T. Jones,Helena Kuivaniemi,James R. Elmore,Mattias Johansson,James McKay,Ghislaine Scelo,Robert Carreras-Torres,Valerie Gaborieau,Paul Brennan,Paige M. Bracci,Rachel E. Neale,Sara H. Olson,Steven Gallinger,Donghui Li,Gloria M. Petersen,Harvey A. Risch,Alison P. Klein,Jiali Han,Christian C. Abnet,Neal D. Freedman,Philip R. Taylor,John M. Maris,Katja K.H. Aben,Lambertus A. Kiemeney,Sita H. Vermeulen,John K. Wiencke,Kyle M. Walsh,Margaret Wrensch,Terri Rice,Clare Turnbull,Kevin Litchfield,Lavinia Paternoster,Marie Standl,Gonçalo R. Abecasis,John Paul SanGiovanni,Yong Li,Vladan Mijatovic,Yadav Sapkota,Siew-Kee Low,Krina T. Zondervan,Grant W. Montgomery,Dale R. Nyholt,David A. van Heel,Karen A. Hunt,Dan E. Arking,Foram N. Ashar,Nona Sotoodehnia,Daniel Woo,Jonathan Rosand,Mary E. Comeau,W. Mark Brown,Edwin K. Silverman,John E. Hokanson,Michael H. Cho,Jennie Hui,Manuel A. R. Ferreira,Philip J. Thompson,Alanna C. Morrison,Janine F. Felix,Nicholas L. Smith,Angela M. Christiano,Lynn Petukhova,Regina C. Betz,Xing Fan,Xuejun Zhang,Caihong Zhu,Carl D. Langefeld,Susan D. Thompson,Feijie Wang,Xu Lin,David A. Schwartz,Tasha E. Fingerlin,Jerome I. Rotter,Mary Frances Cotch,Richard A. Jensen,Matthias Munz,Henrik Dommisch,Arne S. Schaefer,Fang Han,Hanna Ollila,Ryan P. Hillary,Omar M. E. Albagha,Stuart H. Ralston,Chenjie Zeng,Wei Zheng,Xiao-Ou Shu,André Reis,Steffen Uebe,Ulrike Hüffmeier,Yoshiya Kawamura,Takeshi Otowa,Tsukasa Sasaki,Martin L. Hibberd,Sonia Davila,Gang Xie,Katherine A. Siminovitch,Jin-Xin Bei,Yi Xin Zeng,Asta Försti,Bowang Chen,Stefano Landi,Andre Franke,Annegret Fischer,David Ellinghaus,Carlos Flores,Imre Noth,Shwu-Fan Ma,Jia Nee Foo,Jianjun Liu,Jong-Won Kim,David G. Cox,Olivier Delattre,Olivier Mirabeau,Christine F. Skibola,Clara S. Tang,Merce Garcia-Barcelo,Kai-Ping Chang,Wen-Hui Su,Yu-Sun Chang,Nicholas G. Martin,Scott D. Gordon,Tracey D. Wade,Chaeyoung Lee,Michiaki Kubo,Pei-Chieng Cha,Yusuke Nakamura,Daniel Levy,Masayuki Kimura,Shih-Jen Hwang,Steven C. Hunt,Tim D. Spector,Nicole Soranzo,Ani Manichaikul,R. Graham Barr,Bratati Kahali,Elizabeth K. Speliotes,Laura M. Yerges-Armstrong,Ching-Yu Cheng,Jost B. Jonas,Tien Yin Wong,Isabella Fogh,Kuang Lin,John Powell,Kenneth Rice,Caroline L Relton,Richard M. Martin,George Davey Smith +197 more
TL;DR: It is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases, as well as single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.
Journal ArticleDOI
Predicting disease recurrence in patients with previous unprovoked venous thromboembolism: a proposed prediction score (DASH).
A. Tosetto,Alfonso Iorio,Maura Marcucci,Trevor Baglin,Mary Cushman,Sabine Eichinger,Gualtiero Palareti,Daniela Poli,Rc Tait,James D. Douketis +9 more
TL;DR: This data indicates that in patients with unprovoked venous thromboembolism, the optimal duration of anticoagulation is anchored on estimating the risk of disease recurrence, and this work contributes to this understanding.
Journal ArticleDOI
Patterns of Rare and Abundant Marine Microbial Eukaryotes
Ramiro Logares,Stéphane Audic,Stéphane Audic,David Bass,Lucie Bittner,Lucie Bittner,Lucie Bittner,Christophe Boutte,Christophe Boutte,Richard Christen,Richard Christen,Jean-Michel Claverie,Johan Decelle,Johan Decelle,John R. Dolan,Micah Dunthorn,Bente Edvardsen,Angélique Gobet,Angélique Gobet,Wiebe H. C. F. Kooistra,Frédéric Mahé,Frédéric Mahé,Frédéric Mahé,Fabrice Not,Fabrice Not,Hiroyuki Ogata,Hiroyuki Ogata,Jan Pawlowski,Massimo C. Pernice,Sarah Romac,Sarah Romac,Kamran Shalchian-Tabrizi,Nathalie Simon,Nathalie Simon,Thorsten Stoeck,Sébastien Santini,Raffaele Siano,Patrick Wincker,Adriana Zingone,Thomas A. Richards,Colomban de Vargas,Colomban de Vargas,Ramon Massana +42 more
TL;DR: The authors investigated abundant and rare subcommunities of marine microbial eukaryotes, a crucial group of organisms that remains among the least-explored biodiversity components of the biosphere.
Journal ArticleDOI
Optimal stomatal behaviour around the world
Yan-Shih Lin,Belinda E. Medlyn,Remko A. Duursma,I. Colin Prentice,I. Colin Prentice,Han Wang,Sofia Baig,Derek Eamus,Víctor Resco de Dios,Patrick J. Mitchell,David S. Ellsworth,Maarten Op de Beeck,Göran Wallin,Johan Uddling,Lasse Tarvainen,Maj-Lena Linderson,Lucas A. Cernusak,Jesse B. Nippert,Troy W. Ocheltree,David T. Tissue,Nicolas Martin-StPaul,Alistair Rogers,Jeffrey M. Warren,Paolo De Angelis,Kouki Hikosaka,Qingmin Han,Yusuke Onoda,Teresa E. Gimeno,Craig V. M. Barton,Jonathan Bennie,Damien Bonal,Alexandre Bosc,Alexandre Bosc,Markus Löw,Cate Macinins-Ng,Ana Rey,Lucy Rowland,Samantha A. Setterfield,Sabine Tausz-Posch,Joana Zaragoza-Castells,M. S. J. Broadmeadow,John E. Drake,Michael Freeman,Oula Ghannoum,Lindsay B. Hutley,Jeff W. G. Kelly,Kihachiro Kikuzawa,Pasi Kolari,Kohei Koyama,Kohei Koyama,Jean-Marc Limousin,Patrick Meir,Antonio Carlos Lola da Costa,Teis Nørgaard Mikkelsen,Norma Salinas,Norma Salinas,Wei Sun,Lisa Wingate +57 more
TL;DR: In this paper, the authors present a database of globally distributed stomatal conductance (g(s) obtained in the field for a wide range of plant functional types (PFTs) and biomes.
Journal ArticleDOI
Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin-angiotensin-aldosterone inhibitors.
Iziah E Sama,Alice Ravera,Alice Ravera,Bernadet T. Santema,Harry van Goor,Jozine M. ter Maaten,John G.F. Cleland,Michiel Rienstra,Alexander W. Friedrich,Nilesh J. Samani,Leong L. Ng,Kenneth Dickstein,Kenneth Dickstein,Chim C. Lang,Gerasimos Filippatos,Gerasimos Filippatos,Stefan D. Anker,Piotr Ponikowski,Marco Metra,Dirk J. van Veldhuisen,Adriaan A. Voors +20 more
TL;DR: In this article, the authors measured ACE2 concentrations in 1485 men and 537 women with heart failure (index cohort) and found that the strongest predictor of elevated concentrations of ACE2 in both cohorts was male sex.