G
Guido Kroemer
Researcher at Institut Gustave Roussy
Publications - 1546
Citations - 294816
Guido Kroemer is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 236, co-authored 1404 publications receiving 246571 citations. Previous affiliations of Guido Kroemer include Karolinska Institutet & Spanish National Research Council.
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Trial Watch: Toll-like receptor agonists in cancer immunotherapy
Melody Smith,Elena García-Martínez,Michael R. Pitter,Jitka Fucikova,Radek Spisek,Laurence Zitvogel,Guido Kroemer,Lorenzo Galluzzi,Lorenzo Galluzzi +8 more
TL;DR: Recent preclinical and clinical advances in the development of TLR agonists for cancer therapy are summarized.
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Mechanisms of apoptotic phosphatidylserine exposure
Guillermo Mariño,Guido Kroemer +1 more
TL;DR: In a recent paper in Science, Nagata and coworkers reveal that the scramblases Xkr8 and its C. elegans ortholog, CED-8, are activated by caspase cleavage in apoptotic cells.
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Autophagy in acute brain injury
TL;DR: The context-specific impact of autophagy on non-infectious acute brain injury is dissected, emphasizing the possible therapeutic application of pharmacological activators and inhibitors of this catabolic process for neuroprotection.
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Autophagic removal of micronuclei.
Santiago Rello-Varona,Delphine Lissa,Shensi Shen,Mireia Niso-Santano,Laura Senovilla,Guillermo Mariño,Ilio Vitale,Mohamed Jemaà,Francis Harper,Gérard Pierron,Maria Castedo,Guido Kroemer +11 more
TL;DR: Results indicate that micron nuclei can be subjected to autophagic degradation and it can be speculated that removal of micronuclei may contribute to the genome-stabilizing effects of autophagy.
Journal Article
Prion diseases are efficiently transmitted by blood transfusion in sheep. Commentary
Laurence Zitvogel,Guido Kroemer,David J. Anstee,Fiona Houston,Sandra McCutcheon,Wilfred Goldmann,Angela Chong,James Foster,Sílvia Sisó,Lorenzo González,Martin Jeffrey,Nora Hunter +11 more
TL;DR: In this paper, the authors used sheep as a model for studying transmission of variant Creutzfeld-Jakob disease by blood products in humans and found high transmission rates and relatively short and consistent incubation periods in clinically positive recipients.