G
Guido Kroemer
Researcher at Institut Gustave Roussy
Publications - 1546
Citations - 294816
Guido Kroemer is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 236, co-authored 1404 publications receiving 246571 citations. Previous affiliations of Guido Kroemer include Karolinska Institutet & Spanish National Research Council.
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Mitochondria as regulators of apoptosis: doubt no more
TL;DR: The implication of mitochondria in apoptosis has important consequences for the understanding of the normal physiology of apoptosis, its deregulation in cancer and degenerative diseases, and the development of novel cytotoxic and cytoprotective drugs.
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Heat shock proteins: endogenous modulators of apoptotic cell death.
TL;DR: A review of apoptosis-regulatory function of HSPs concludes that HSP27 and HSP70 may participate in carcinogenesis and should be considered as suspects in the development of cancer.
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Mitochondrial permeability transition is a central coordinating event of apoptosis
Philippe Marchetti,Maria Castedo,Santos A. Susin,N Zamzami,Tamara Hirsch,Antonio Macho,Astrid Haeffner,Frangois Hirsch,Maurice Geuskens,Guido Kroemer +9 more
TL;DR: Testing the effect of a specific inhibitor of PT, bongkrekic acid (BA), a ligand of the mitochondrial adenine nucleotide translocator, on a prototypic model of apoptosis glucocorticoid-induced thymocyte death suggests that a number of apoptotic phenomena are secondary to PT.
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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
Lorenzo Galluzzi,J M Bravo-San Pedro,Ilio Vitale,Stuart A. Aaronson,John M. Abrams,Dieter Adam,Emad S. Alnemri,Lucia Altucci,David W. Andrews,Margherita Annicchiarico-Petruzzelli,Eric H. Baehrecke,Nicolas G. Bazan,Mathieu J.M. Bertrand,Mathieu J.M. Bertrand,Katiuscia Bianchi,Katiuscia Bianchi,Mikhail V. Blagosklonny,Klas Blomgren,Christoph Borner,Dale E. Bredesen,Dale E. Bredesen,Catherine Brenner,Catherine Brenner,Michelangelo Campanella,Eleonora Candi,Francesco Cecconi,Francis Ka-Ming Chan,Navdeep S. Chandel,Emily H. Cheng,Jerry E. Chipuk,John A. Cidlowski,Aaron Ciechanover,Ted M. Dawson,Valina L. Dawson,V De Laurenzi,R De Maria,Klaus-Michael Debatin,N. Di Daniele,Vishva M. Dixit,Brian David Dynlacht,Wafik S. El-Deiry,Gian Maria Fimia,Richard A. Flavell,Simone Fulda,Carmen Garrido,Marie-Lise Gougeon,Douglas R. Green,Hinrich Gronemeyer,György Hajnóczky,J M Hardwick,Michael O. Hengartner,Hidenori Ichijo,Bertrand Joseph,Philipp J. Jost,Thomas Kaufmann,Oliver Kepp,Daniel J. Klionsky,Richard A. Knight,Richard A. Knight,Sharad Kumar,Sharad Kumar,John J. Lemasters,Beth Levine,Beth Levine,Andreas Linkermann,Stuart A. Lipton,Richard A. Lockshin,Carlos López-Otín,Enrico Lugli,Frank Madeo,Walter Malorni,Jean-Christophe Marine,Seamus J. Martin,J-C Martinou,Jan Paul Medema,Pascal Meier,Sonia Melino,Noboru Mizushima,Ute M. Moll,Cristina Muñoz-Pinedo,Gabriel Núñez,Andrew Oberst,Theocharis Panaretakis,Josef M. Penninger,Marcus E. Peter,Mauro Piacentini,Paolo Pinton,Jochen H. M. Prehn,Hamsa Puthalakath,Gabriel A. Rabinovich,Kodi S. Ravichandran,Rosario Rizzuto,Cecília M. P. Rodrigues,David C. Rubinsztein,Thomas Rudel,Yufang Shi,Hans-Uwe Simon,Brent R. Stockwell,Brent R. Stockwell,Gyorgy Szabadkai,Gyorgy Szabadkai,Stephen W.G. Tait,H. L. Tang,Nektarios Tavernarakis,Nektarios Tavernarakis,Yoshihide Tsujimoto,T Vanden Berghe,T Vanden Berghe,Peter Vandenabeele,Peter Vandenabeele,Andreas Villunger,Erwin F. Wagner,Henning Walczak,Eileen White,W. G. Wood,Junying Yuan,Zahra Zakeri,Boris Zhivotovsky,Boris Zhivotovsky,Gerry Melino,Gerry Melino,Guido Kroemer +121 more
TL;DR: The Nomenclature Committee on Cell Death formulates a set of recommendations to help scientists and researchers to discriminate between essential and accessory aspects of cell death.
Journal ArticleDOI
Broadening horizons: the role of ferroptosis in cancer.
TL;DR: In this paper, the key molecular mechanisms of ferroptosis, including crosstalk with tumour-associated signalling pathways, and discuss potential therapeutic applications of the process are presented.