G
Guido Kroemer
Researcher at Institut Gustave Roussy
Publications - 1546
Citations - 294816
Guido Kroemer is an academic researcher from Institut Gustave Roussy. The author has contributed to research in topics: Programmed cell death & Apoptosis. The author has an hindex of 236, co-authored 1404 publications receiving 246571 citations. Previous affiliations of Guido Kroemer include Karolinska Institutet & Spanish National Research Council.
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Tumor-infiltrating regulatory T cells: phenotype, role, mechanism of expansion in situ and clinical significance.
Corinne Tanchot,Magali Terme,Magali Terme,Hélène Péré,Hélène Péré,Thi Tran,Thi Tran,N. Benhamouda,N. Benhamouda,Marius Strioga,C. Banissi,C. Banissi,Lorenzo Galluzzi,Guido Kroemer,Eric Tartour,Eric Tartour +15 more
TL;DR: The phenotype, function and clinical significance of various Treg subsets are discussed, including FOXP3+ regulatory T cells, which accumulate within neoplastic lesions as a result of several distinct mechanisms, including increased infiltration, local expansion, survival advantage and in situ development from conventional CD4+ cells.
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Trial watch: Peptide-based vaccines in anticancer therapy.
Lucillia Bezu,Oliver Kepp,Giulia Cerrato,Jonathan Pol,Jitka Fucikova,Radek Spisek,Laurence Zitvogel,Laurence Zitvogel,Guido Kroemer,Lorenzo Galluzzi,Lorenzo Galluzzi +10 more
TL;DR: Preclinical and clinical progress in the use of peptide-based vaccines as anticancer therapeutics is reviewed, with particular focus on personalized peptide vaccination.
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Erratum: Molecular mechanisms of cell death: Central implication of ATP synthase in mitochondrial permeability transition (Oncogene (2015) 34 (1475-1486 ) DOI: 10.1038/onc.2014.96)
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Immunogenicity of anthracyclines: moving towards more personalized medicine.
TL;DR: In this paper, the effects of anthracyclines on the host immune system and how this knowledge can be exploited for anticancer therapy are discussed. But, the authors do not discuss how to exploit this knowledge to improve the efficacy of chemotherapy.
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Interrelation between polyploidization and megakaryocyte differentiation : a gene profiling approach
Hana Raslova,Hana Raslova,Audrey Kauffmann,Dalila Sekkaı̈,Dalila Sekkaı̈,Hugues Ripoche,Frédéric Larbret,Frédéric Larbret,Thomas Robert,Diana Tronik-Le Roux,Guido Kroemer,Guido Kroemer,Najet Debili,Najet Debili,Philippe Dessen,Vladimir Lazar,William Vainchenker,William Vainchenker +17 more
TL;DR: The results suggest that MK polyploidization per se does not regulate gene expression but is intrinsically included in the differentiation process.