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Jonine Figueroa

Researcher at National Institutes of Health

Publications -  9
Citations -  1541

Jonine Figueroa is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Breast cancer & Genome-wide association study. The author has an hindex of 9, co-authored 9 publications receiving 1388 citations. Previous affiliations of Jonine Figueroa include University of Edinburgh & McGill University.

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Journal ArticleDOI

RAD51B in Familial Breast Cancer

Liisa M. Pelttari, +115 more
- 05 May 2016 - 
TL;DR: It is suggested that loss-of-function mutations in RAD 51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk.
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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

Roger L. Milne, +512 more
- 23 Oct 2017 - 
TL;DR: A genome-wide association study (GWAS) of predominantly estrogen receptor (ER)-positive disease and BRCA1 mutation carrier GWAS observed consistent associations with ER-negative disease for 105 susceptibility variants identified by other studies, which explain approximately 16% of the familial risk of this breast cancer subtype.
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Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

Yan Guo, +117 more
- 23 Aug 2016 - 
TL;DR: BMI predicted by genome-wide association studies (GWAS)-identified variants is inversely associated with the risk of both pre- and postmenopausal breast cancer, differs from the positive association reported from studies using measured adult BMI.
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Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

Amanda B. Spurdle, +208 more
- 23 Dec 2014 - 
TL;DR: Large pathology datasets accrued by the Consortium of Investigators of Modifiers of BRCA1/2 and the Breast Cancer Association Consortium are analyzed to reassess histopathological predictors of B RCA1 and BRCa2 mutation status, and robust likelihood ratio estimates for statistical modeling are refined.
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Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Fergus J. Couch, +256 more
- 27 Apr 2016 - 
TL;DR: Four previously unidentified loci are identified including two loci at 13q22 near KLF5, a 2p23.2 locus near WDR43 and a 2q33 locus close to PPIL3 that display genome-wide significant associations with ER-negative breast cancer.