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Institution

Temple University

EducationPhiladelphia, Pennsylvania, United States
About: Temple University is a education organization based out in Philadelphia, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 32154 authors who have published 64375 publications receiving 2219828 citations.


Papers
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Journal ArticleDOI
TL;DR: The issues surrounding the genetic effects of pollution are reviewed, the technical approaches that can be used to address these issues are summarized, and examples of studies that have addressed some of them are provided.
Abstract: The conservation of genetic diversity has emerged as one of the central issues in conservation biology. Although researchers in the areas of evolutionary biology, population management, and conservation biology routinely investigate genetic variability in natural populations, only a handful of studies have addressed the effects of chemical contamination on population genetics. Chemical contamination can cause population reduction by the effects of somatic and heritable mutations, as well as non-genetic modes of toxicity. Stochastic processes in small populations, increased mutation load, and the phenomenon of mutational meltdown are compounding factors that cause reduced fitness and accelerate the process of population extirpation. Although the original damage caused by chemical contaminants is at the molecular level, there are emergent effects at the level of populations, such as the loss of genetic diversity, that are not predictable based solely on knowledge of the mechanism of toxicity of the chemical contaminants. Therefore, the study of evolutionary toxicology, which encompasses the population-genetic effects of environmental contaminants, should be an important focus of ecotoxicology. This paper reviews the issues surrounding the genetic effects of pollution, summarizes the technical approaches that can be used to address these issues, and provides examples of studies that have addressed some of them.

401 citations

Journal ArticleDOI
TL;DR: To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR).
Abstract: BACKGROUND: Critical examination of the quality and validity of available allergic rhinitis (AR) literature is necessary to improve understanding and to appropriately translate this knowledge to clinical care of the AR patient. To evaluate the existing AR literature, international multidisciplinary experts with an interest in AR have produced the International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR). METHODS: Using previously described methodology, specific topics were developed relating to AR. Each topic was assigned a literature review, evidence-based review (EBR), or evidence-based review with recommendations (EBRR) format as dictated by available evidence and purpose within the ICAR:AR document. Following iterative reviews of each topic, the ICAR:AR document was synthesized and reviewed by all authors for consensus. RESULTS: The ICAR:AR document addresses over 100 individual topics related to AR, including diagnosis, pathophysiology, epidemiology, disease burden, risk factors for the development of AR, allergy testing modalities, treatment, and other conditions/comorbidities associated with AR. CONCLUSION: This critical review of the AR literature has identified several strengths; providers can be confident that treatment decisions are supported by rigorous studies. However, there are also substantial gaps in the AR literature. These knowledge gaps should be viewed as opportunities for improvement, as often the things that we teach and the medicine that we practice are not based on the best quality evidence. This document aims to highlight the strengths and weaknesses of the AR literature to identify areas for future AR research and improved understanding.

401 citations

Journal ArticleDOI
TL;DR: Interference between the short- and long-range (Coulomb) couplings gives rise to a host of new aggregate types, referred to as HH, HJ, JH, and JJ aggregates, with distinct photophysical properties, which can be exploited for electronic materials design.
Abstract: ConspectusThe transport and photophysical properties of organic molecular aggregates, films, and crystals continue to receive widespread attention, driven mainly by expanding commercial applications involving display and wearable technologies as well as the promise of efficient, large-area solar cells. The main blueprint for understanding how molecular packing impacts photophysical properties was drafted over five decades ago by Michael Kasha. Kasha showed that the Coulombic coupling between two molecules, as determined by the alignment of their transition dipoles, induces energetic shifts in the main absorption spectral peak and changes in the radiative decay rate when compared to uncoupled molecules. In H-aggregates, the transition dipole moments align “side-by-side” leading to a spectral blue-shift and suppressed radiative decay rate, while in J-aggregates, the transition dipole moments align “head-to-tail” leading to a spectral red-shift and an enhanced radiative decay rate. Although many examples of ...

400 citations

Journal ArticleDOI
TL;DR: Adolescents who perceived their parents as being nonauthoritative were more likely than their peers to attribute achievement outcomes to external causes or to low ability and the higher the proportion of dysfunctional attributions made for academic successes and failures, the lower the levels of classroom engagement and homework 1 year later.
Abstract: This article examined the contemporaneous and predictive relations between parenting styles, adolescents' attributions, and 4 educational outcomes. Data were collected from adolescents attending 6 high schools in California and 3 high schools in Wisconsin during the 1987-1988 and 1988-1989 school years. The results of path analyses partially confirmed the central hypotheses. Adolescents who perceived their parents as being nonauthoritative were more likely than their peers to attribute achievement outcomes to external causes or to low ability. Furthermore, the higher the proportion of dysfunctional attributions made for academic successes and failures, the lower the levels of classroom engagement and homework 1 year later. Although adolescents' attributional style provided a bridge between parenting style and 2 educational outcomes, it did not fully explain the impact of parenting on those outcomes. Additional analyses within gender and ethnic subgroups reinforced the overall pattern of findings observed within the entire sample.

400 citations

Journal ArticleDOI
TL;DR: Castells et al. as discussed by the authors argue that the global digital divide, as measured by cross-national differences in Internet use, is the result of the economic, regulatory and sociopolitical characteristics of countries and their evolution over time.
Abstract: We argue that the global digital divide, as measured by cross-national differences in Internet use, is the result of the economic, regulatory and sociopolitical characteristics of countries and their evolution over time. We predict Internet use to increase with worldsystem status, privatization and competition in the telecommunications sector, democracy and cosmopolitanism. Using data on 118 countries from 1997 through 2001, we find relatively robust support for each of our hypotheses. We conclude by exploring the implications of this new, powerful communication medium for the global political economy and for the spread of democracy around the world. The Internet has developed unevenly throughout the world, creating what has become known as the “global digital divide” (Castells 2001; Kirkman et al. 2002; Mosaic Group 1998; Norris 2001; Rogers 2001). The number of Internet users is one of the most widely used indicators of development of this emerging medium of communication. Less than 10 percent of the world’s population uses the Internet, and the gap between developed and developing countries has continued to widen since the early 1990s (see Figure 1). Differences by country are remarkable. Statistics compiled by the International Telecommunication Union as of the end of 2002 indicate that Internet use as a proportion of the population ranges from less than one percent in many underdeveloped African, Central American, and South Asian countries to between 50 and 60 percent in Iceland, the United States, Scandinavia, Singapore or South Korea (ITU 2003).1 The growth of the Internet has captured the imagination of users, policymakers, entrepreneurs, corporate managers, military strategists, social commentators, scholars, and journalists. Some early optimistic analyses envisioned the Internet as a “decentralizing, globalizing, harmonizing, and empowering” medium (Negroponte 1995:229), as a new communication technology that would bring about a “smaller, more open world.” (Tapscott and Caston 1993:313) The most enthusiastic visionaries have argued that the Internet means the “triumph over time and space,” the rise of the “netizen,” and the crowning of the “customer as sovereign” (Gilder 2000). According to the cyber-optimists, the Internet can create a public sphere in Habermas’s (1989) sense, one that is not regulated by the state or by commercial interests but rather owned and controlled by the participants themselves (Schneider 1996). While some of the cyber-optimists recognized the looming issue of inequality in access to the Internet (e.g. Tapscott and Caston 1993:312), it was not until the late 1990s that international organizations, governments, think tanks, and universities started to warn about the existence of a yawning digital divide, both within and across countries (e.g., U.S.

400 citations


Authors

Showing all 32360 results

NameH-indexPapersCitations
Robert J. Lefkowitz214860147995
Rakesh K. Jain2001467177727
Virginia M.-Y. Lee194993148820
Yury Gogotsi171956144520
Timothy A. Springer167669122421
Ralph A. DeFronzo160759132993
James J. Collins15166989476
Robert J. Glynn14674888387
Edward G. Lakatta14685888637
Steven Williams144137586712
Peter Buchholz143118192101
David Goldstein1411301101955
Scott D. Solomon1371145103041
Donald B. Rubin132515262632
Jeffery D. Molkentin13148261594
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202366
2022335
20213,475
20203,281
20193,166
20183,019