C
Cristina Menni
Researcher at King's College London
Publications - 210
Citations - 23677
Cristina Menni is an academic researcher from King's College London. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 58, co-authored 180 publications receiving 16556 citations. Previous affiliations of Cristina Menni include University of London & University of Milan.
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Journal ArticleDOI
Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain
Cristina Menni,Matthew A. Jackson,Tess Pallister,Claire J. Steves,Tim D. Spector,Ana M. Valdes,Ana M. Valdes +6 more
TL;DR: High gut microbiome diversity, high-fibre intake and OTUs implicated in animal models of improved energy metabolism are all correlated with lower term weight gain in humans independently of calorie intake and other confounders.
Journal ArticleDOI
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
Praveen Surendran,Fotios Drenos,Robin Young,Helen R. Warren,James P. Cook,Alisa K. Manning,Niels Grarup,Xueling Sim,Daniel R. Barnes,Kate Witkowska,James R Staley,Vinicius Tragante,Taru Tukiainen,Hanieh Yaghootkar,Nicholas Masca,Daniel F. Freitag,Teresa Ferreira,Olga Giannakopoulou,Andrew Tinker,Magdalena Harakalova,Evelin Mihailov,Chunyu Liu,Aldi T. Kraja,Sune F. Nielsen,Asif Rasheed,Maria Samuel,Wei Zhao,Lori L. Bonnycastle,Anne U. Jackson,Narisu Narisu,Amy J. Swift,Lorraine Southam,Jonathan Marten,Jeroen R. Huyghe,Alena Stančáková,Cristiano Fava,Therese Ohlsson,Angela Matchan,Kathleen Stirrups,Jette Bork-Jensen,Anette P. Gjesing,Jukka Kontto,Markus Perola,Susan Shaw-Hawkins,Aki S. Havulinna,He Zhang,Louise A. Donnelly,Christopher J. Groves,N. William Rayner,Matt Neville,Neil R. Robertson,Andrianos M. Yiorkas,Karl-Heinz Herzig,Eero Kajantie,Weihua Zhang,Sara M. Willems,Lars Lannfelt,Giovanni Malerba,Nicole Soranzo,Elisabetta Trabetti,Niek Verweij,Evangelos Evangelou,Alireza Moayyeri,Anne-Claire Vergnaud,Christopher P. Nelson,Alaitz Poveda,Tibor V. Varga,Muriel J. Caslake,Anton J. M. de Craen,Stella Trompet,Jian'an Luan,Robert A. Scott,Sarah E. Harris,David C. Liewald,Riccardo E. Marioni,Cristina Menni,Aliki-Eleni Farmaki,Göran Hallmans,Frida Renström,Jennifer E. Huffman,Maija Hassinen,Stephen Burgess,Ramachandran S. Vasan,Janine F. Felix,Maria Uria-Nickelsen,Anders Mälarstig,Dermot F. Reilly,Maarten Hoek,Thomas F. Vogt,Honghuang Lin,Wolfgang Lieb,Matthew Traylor,Hugh S. Markus,Heather M. Highland,Anne E. Justice,Eirini Marouli,Jaana Lindström,Matti Uusitupa,Pirjo Komulainen,Timo A. Lakka,Rainer Rauramaa,Ozren Polasek,Igor Rudan,Olov Rolandsson,Paul W. Franks,George Dedoussis,Tim D. Spector,Pekka Jousilahti,Satu Männistö,Ian J. Deary,John M. Starr,Claudia Langenberg,Nicholas J. Wareham,Morris Brown,Anna F. Dominiczak,John M. C. Connell,J. Wouter Jukema,Naveed Sattar,Ian Ford,Chris J. Packard,Tõnu Esko,Reedik Mägi,Andres Metspalu,Rudolf A. de Boer,Peter van der Meer,Pim van der Harst,Giovanni Gambaro,Erik Ingelsson,Lars Lind,Paul I.W. de Bakker,Mattijs E. Numans,Ivan Brandslund,Cramer Christensen,Eva Rabing Brix Petersen,Eeva Korpi-Hyövälti,Heikki Oksa,John C. Chambers,Jaspal S. Kooner,Alexandra I. F. Blakemore,Steve Franks,Marjo-Riitta Järvelin,Lise Lotte N. Husemoen,Allan Linneberg,Tea Skaaby,Betina H. Thuesen,Fredrik Karpe,Jaakko Tuomilehto,Alex S. F. Doney,Andrew D. Morris,Colin N. A. Palmer,Oddgeir L. Holmen,Kristian Hveem,Cristen J. Willer,Tiinamaija Tuomi,Leif Groop,Annemari Käräjämäki,Aarno Palotie,Samuli Ripatti,Veikko Salomaa,Dewan S. Alam,Abdulla Al Shafi Majumder,Emanuele Di Angelantonio,Rajiv Chowdhury,Mark I. McCarthy,Neil Poulter,Alice Stanton,Peter S. Sever,Philippe Amouyel,Dominique Arveiler,Stefan Blankenberg,Jean Ferrières,Frank Kee,Kari Kuulasmaa,Martina Müller-Nurasyid,Giovanni Veronesi,Jarmo Virtamo,Panos Deloukas,Paul Elliott,Eleftheria Zeggini,Sekar Kathiresan,Olle Melander,Johanna Kuusisto,Markku Laakso,Sandosh Padmanabhan,David J. Porteous,Caroline Hayward,Generation Scotland,Francis S. Collins,Karen L. Mohlke,Torben Hansen,Oluf Pedersen,Michael Boehnke,Heather M. Stringham,Philippe M. Frossard,Christopher Newton-Cheh,Martin D. Tobin,Børge G. Nordestgaard,Mark J. Caulfield,Anubha Mahajan,Andrew P. Morris,Maciej Tomaszewski,Nilesh J. Samani,Danish Saleheen,Folkert W. Asselbergs,Cecilia M. Lindgren,John Danesh,Louise V. Wain,Adam S. Butterworth,Joanna M. M. Howson,Patricia B. Munroe +209 more
TL;DR: Thirty new blood pressure– or hypertension-associated genetic regions in the general population are identified, including 3 rare missense variants in RBM47, COL21A1 and RRAS with larger effects than common variants.
Journal ArticleDOI
The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis
Mario Roederer,Lydia Quaye,Massimo Mangino,Massimo Mangino,Margaret H. Beddall,Yolanda D. Mahnke,Pratip K. Chattopadhyay,Isabella Tosi,Isabella Tosi,Luca Napolitano,Manuela Terranova Barberio,Cristina Menni,Federica Villanova,Federica Villanova,Paola Di Meglio,Tim D. Spector,Frank O. Nestle,Frank O. Nestle +17 more
TL;DR: This data set reveals traits associated with loci known to confer autoimmune susceptibility, providing mechanistic hypotheses linking immune traits with the etiology of disease, and establishes a bioresource that links genetic control elements associated with normal immune traits to common autoimmune and infectious diseases.
Journal ArticleDOI
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Symen Ligthart,Ahmad Vaez,Urmo Võsa,Maria G. Stathopoulou,P. De Vries,Bram P. Prins,P. J. van der Most,Toshiko Tanaka,Elnaz Naderi,Lynda M. Rose,Ying Wu,Robert Karlsson,Maja Barbalić,Honghuang Lin,René Pool,Gu Zhu,Aurélien Macé,C Sidore,Stella Trompet,Massimo Mangino,Maria Sabater-Lleal,John P. Kemp,Ali Abbasi,Tim Kacprowski,Niek Verweij,Albert V. Smith,Tao Huang,Carola Marzi,Mary F. Feitosa,Kurt Lohman,Marcus E. Kleber,Yuri Milaneschi,Christine M. Mueller,M Huq,Efthymia Vlachopoulou,Lyytikäinen L-P.,Christopher Oldmeadow,Joris Deelen,Markus Perola,Jing Hua Zhao,Bjarke Feenstra,Marzyeh Amini,Jari Lahti,Katharina E. Schraut,Myriam Fornage,Bhoom Suktitipat,Chen W-M.,Xiaohui Li,Teresa Nutile,Giovanni Malerba,Jian'an Luan,Tom Bak,Nicholas J. Schork,Elisabeth Thiering,Anubha Mahajan,Riccardo E. Marioni,Evelin Mihailov,Joel Eriksson,Ayse Bilge Ozel,Weihua Zhang,Maria Nethander,Cheng Y-C.,Stella Aslibekyan,Wei Ang,Ilaria Gandin,Loic Yengo,Laura Portas,Charles Kooperberg,Edith Hofer,Kumar B. Rajan,Claudia Schurmann,W. den Hollander,Tarunveer S. Ahluwalia,Jing Zhao,Draisma Hhm.,Ian Ford,Nicholas J. Timpson,Alexander Teumer,Hongyan Huang,Simone Wahl,Yongmei Liu,Jinyan Huang,Uh H-W.,Frank Geller,Peter K. Joshi,Lisa R. Yanek,Elisabetta Trabetti,Benjamin Lehne,Diego Vozzi,M Verbanck,Ginevra Biino,Yasaman Saba,Ingrid Meulenbelt,Jeffery R. O'Connell,Markku Laakso,Franco Giulianini,Magnusson Pke.,Christie M. Ballantyne,J-J Hottenga,Grant W. Montgomery,Fernando Rivadineira,Rico Rueedi,Maristella Steri,Herzig K-H.,David J. Stott,Cristina Menni,Mattias Frånberg,B. St Pourcain,Stephan B. Felix,Tune H. Pers,Bakker Sjl.,Peter Kraft,Annette Peters,Dhananjay Vaidya,Graciela Delgado,Jan H. Smit,V Großmann,Juha Sinisalo,Ilkka Seppälä,Stephen R. Williams,Elizabeth G. Holliday,Matthijs Moed,Claudia Langenberg,Katri Räikkönen,Jun Ding,Harry Campbell,Michèle M. Sale,Chen Y-Di.,Chen Y-Di.,Alan James,Daniela Ruggiero,Nicole Soranzo,Catharina A. Hartman,Erin N. Smith,Gerald S. Berenson,Christian Fuchsberger,Dena G. Hernandez,Tiesler Cmt.,Vilmantas Giedraitis,D C Liewald,Krista Fischer,Dan Mellström,Anders Larsson,Yajuan Wang,William R. Scott,Mattias Lorentzon,John Beilby,Kathleen A. Ryan,Craig E. Pennell,Dragana Vuckovic,Beverley Balkau,Maria Pina Concas,Reinhold Schmidt,C. F. Mendes de Leon,C. F. Mendes de Leon,Erwin P. Bottinger,Margreet Kloppenburg,Lavinia Paternoster,Michael Boehnke,Arthur W. Musk,Gonneke Willemsen,David M. Evans,Madden Paf.,Mika Kähönen,Zoltán Kutalik,Magdalena Zoledziewska,Ville Karhunen,Stephen B. Kritchevsky,Naveed Sattar,Genevieve Lachance,Robert Clarke,T.B. Harris,Olli T. Raitakari,John Attia,D. van Heemst,Eero Kajantie,Rossella Sorice,Giovanni Gambaro,Robert A. Scott,Andrew A. Hicks,Luigi Ferrucci,M. Standl,Cecilia M. Lindgren,John M. Starr,Magnus Karlsson,Lars Lind,Jun Li,John C. Chambers,Trevor A. Mori,de Geus Ejcn.,A. C. Heath,Nicholas G. Martin,Juha Auvinen,Brendan M. Buckley,de Craen Ajm.,M. Waldenberger,Konstantin Strauch,Thomas Meitinger,R. J. Scott,Mark McEvoy,Marian Beekman,Cristina Bombieri,Paul M. Ridker,Karen L. Mohlke,Nancy L. Pedersen,A C Morrison,Dorret I. Boomsma,John Whitfield,David P. Strachan,Albert Hofman,Peter Vollenweider,Francesco Cucca,Jarvelin M-R.,Joop Jukema,Tim D. Spector,Anders Hamsten,Tanja Zeller,André G. Uitterlinden,Matthias Nauck,Vilmundur Gudnason,Lu Qi,H Grallert,Ingrid B. Borecki,Jerome I. Rotter,W. März,Philipp S. Wild,Lokki M-L.,Michael Boyle,Veikko Salomaa,Mads Melbye,Johan G. Eriksson,James F. Wilson,Penninx Bwjh.,Diane M. Becker,B. B. Worrall,Greg Gibson,Ronald M. Krauss,Marina Ciullo,Gianluigi Zaza,Nicholas J. Wareham,Albertine J. Oldehinkel,Lyle J. Palmer,Sarah S. Murray,Peter P. Pramstaller,Stefania Bandinelli,Joachim Heinrich,Erik Ingelsson,Ian J. Deary,Reedik Mägi,Liesbeth Vandenput,P. van der Harst,Karl C. Desch,Jaspal S. Kooner,Claes Ohlsson,Caroline Hayward,Terho Lehtimäki,Alan R. Shuldiner,Donna K. Arnett,Lawrie J. Beilin,Antonietta Robino,Philippe Froguel,Mario Pirastu,T. Jess,Wolfgang Koenig,Loos Rjf.,Denis A. Evans,Helena Schmidt,George Davey Smith,P E Slagboom,Gudny Eiriksdottir,Andrew P. Morris,Bruce M. Psaty,Russel Tracy,Ilja M. Nolte,Eric Boerwinkle,Sophie Visvikis-Siest,Alexander P. Reiner,Myron D. Gross,J. C. Bis,Lude Franke,Oscar H. Franco,E J Benjamin,Daniel I. Chasman,Josée Dupuis,Harold Snieder,Abbas Dehghan,Behrooz Z. Alizadeh +286 more
TL;DR: In this article, the authors performed two genome-wide association studies (GWASs), on HapMap and 1000 Genomes imputed data, of circulating amounts of CRP by using data from 88 studies comprising 204,402 European individuals.
Journal ArticleDOI
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Yingchang Lu,Felix R. Day,Stefan Gustafsson,Stefan Gustafsson,Martin L. Buchkovich,Jianbo Na,Veronique Bataille,Veronique Bataille,Diana L. Cousminer,Zari Dastani,Alexander W. Drong,Tõnu Esko,David M. Evans,Mario Falchi,Mario Falchi,Mary F. Feitosa,Teresa Ferreira,Åsa K. Hedman,Robin Haring,Robin Haring,Pirro G. Hysi,Mark M. Iles,Anne E. Justice,Stavroula Kanoni,Stavroula Kanoni,Vasiliki Lagou,Rui Li,Xin Li,Adam E. Locke,Chen Lu,Reedik Mägi,John R. B. Perry,Tune H. Pers,Qibin Qi,Marianna Sanna,Marianna Sanna,Ellen M. Schmidt,William R. Scott,William R. Scott,Dmitry Shungin,Dmitry Shungin,Alexander Teumer,Anna A. E. Vinkhuyzen,Ryan W. Walker,Harm-Jan Westra,Mingfeng Zhang,Weihua Zhang,Weihua Zhang,Jing Hua Zhao,Zhihong Zhu,Uzma Afzal,Uzma Afzal,Tarunveer S. Ahluwalia,Stephan J. L. Bakker,Claire Bellis,Amélie Bonnefond,Amélie Bonnefond,Katja Borodulin,Aron S. Buchman,Tommy Cederholm,Audrey C. Choh,Hyung Jin Choi,Joanne E. Curran,Lisette C. P. G. M. de Groot,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Rosalie A. M. Dhonukshe-Rutten,Anke W. Enneman,Elodie Eury,Elodie Eury,Daniel S. Evans,Tom Forsén,Nele Friedrich,Frédéric Fumeron,Melissa E. Garcia,Simone Gärtner,Bok-Ghee Han,Aki S. Havulinna,Caroline Hayward,Dena G. Hernandez,Hans L. Hillege,Till Ittermann,Jack W. Kent,Ivana Kolcic,Tiina Laatikainen,Tiina Laatikainen,Jari Lahti,Irene Mateo Leach,Christine G. Lee,Christine G. Lee,Jong-Young Lee,Tian Liu,Youfang Liu,Stéphane Lobbens,Stéphane Lobbens,Marie Loh,Marie Loh,Leo-Pekka Lyytikäinen,Carolina Medina-Gomez,Karl Michaëlsson,Mike A. Nalls,Carrie M. Nielson,Laticia Oozageer,Laura Pascoe,Lavinia Paternoster,Ozren Polasek,Ozren Polasek,Samuli Ripatti,Samuli Ripatti,Mark A. Sarzynski,Chan Soo Shin,Nina Smolej Narančić,Dominik Spira,Priya Srikanth,Elisabeth Steinhagen-Thiessen,Yun Ju Sung,Karin M. A. Swart,Karin M. A. Swart,Leena Taittonen,Toshiko Tanaka,Emmi Tikkanen,Nathalie van der Velde,Natasja M. van Schoor,Natasja M. van Schoor,Niek Verweij,Alan F. Wright,Lei Yu,Joseph M. Zmuda,Niina Eklund,Terrence Forrester,Niels Grarup,Anne U. Jackson,Kati Kristiansson,Kati Kristiansson,Teemu Kuulasmaa,Johanna Kuusisto,Peter Lichtner,Jian'an Luan,Anubha Mahajan,Satu Männistö,Cameron D. Palmer,Cameron D. Palmer,Janina S. Ried,Robert A. Scott,Alena Stančáková,Peter Wagner,Peter Wagner,Ayse Demirkan,Angela Döring,Vilmundur Gudnason,Douglas P. Kiel,Brigitte Kühnel,Massimo Mangino,Barbara McKnight,Barbara McKnight,Cristina Menni,Jeffrey R. O'Connell,Ben A. Oostra,Alan R. Shuldiner,Alan R. Shuldiner,Kijoung Song,Liesbeth Vandenput,Cornelia M. van Duijn,Peter Vollenweider,Charles C. White,Michael Boehnke,Yvonne Boettcher,Richard S. Cooper,Nita G. Forouhi,Christian Gieger,Harald Grallert,Aroon D. Hingorani,Torben Jørgensen,Torben Jørgensen,Pekka Jousilahti,Mika Kivimäki,Meena Kumari,Markku Laakso,Claudia Langenberg,Allan Linneberg,Amy Luke,Colin A. McKenzie,Aarno Palotie,Aarno Palotie,Aarno Palotie,Oluf Pedersen,Annette Peters,Konstantin Strauch,Bamidele O. Tayo,Nicholas J. Wareham,David A. Bennett,Lars Bertram,Lars Bertram,John Blangero,Matthias Blüher,Claude Bouchard,Harry Campbell,Nam H. Cho,Steven R. Cummings,Stefan A. Czerwinski,Ilja Demuth,Rahel Eckardt,Johan G. Eriksson,Johan G. Eriksson,Luigi Ferrucci,Oscar H. Franco,Philippe Froguel,Philippe Froguel,Ron T. Gansevoort,Torben Hansen,Torben Hansen,Tamara B. Harris,Nicholas D. Hastie,Markku Heliövaara,Albert Hofman,Joanne M. Jordan,Antti Jula,Mika Kähönen,Eero Kajantie,Eero Kajantie,Eero Kajantie,Paul Knekt,Seppo Koskinen,Peter Kovacs,Terho Lehtimäki,Lars Lind,Yongmei Liu,Eric S. Orwoll,Clive Osmond,Markus Perola,Markus Perola,Louis Pérusse,Olli T. Raitakari,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Treva Rice,Fernando Rivadeneira,Igor Rudan,Veikko Salomaa,Thorkild I. A. Sørensen,Michael Stumvoll,Anke Tönjes,Bradford Towne,Gregory J. Tranah,Angelo Tremblay,André G. Uitterlinden,Pim van der Harst,Erkki Vartiainen,Jorma S. A. Viikari,Veronique Vitart,Marie-Claude Vohl,Henry Völzke,Mark Walker,Mark Walker,Henri Wallaschofski,Sarah H Wild,James F. Wilson,Loic Yengo,Loic Yengo,D. Timothy Bishop,Ingrid B. Borecki,Ingrid B. Borecki,John C. Chambers,John C. Chambers,John C. Chambers,L. Adrienne Cupples,Abbas Dehghan,Panos Deloukas,Panos Deloukas,Panos Deloukas,Ghazaleh Fatemifar,Caroline S. Fox,Terrence S. Furey,Lude Franke,Jiali Han,David J. Hunter,Juha Karjalainen,Fredrik Karpe,Robert C. Kaplan,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Mark I. McCarthy,Joanne M. Murabito,Andrew P. Morris,Andrew P. Morris,Julia A. Newton Bishop,Kari E. North,Claes Ohlsson,Ken K. Ong,Inga Prokopenko,J. Brent Richards,Eric E. Schadt,Tim D. Spector,Elisabeth Widen,Cristen J. Willer,Jian Yang,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Karen L. Mohlke,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,John Andrew Pospisilik,M. Carola Zillikens,Cecilia M. Lindgren,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Ruth J. F. Loos +311 more
TL;DR: The loci more strongly associated with BF% showed distinct cross-phenotype association signatures with a range of cardiometabolic traits revealing new insights in the link between adiposity and disease risk.