K
Kari Alitalo
Researcher at University of Helsinki
Publications - 844
Citations - 122462
Kari Alitalo is an academic researcher from University of Helsinki. The author has contributed to research in topics: Angiogenesis & Vascular endothelial growth factor C. The author has an hindex of 174, co-authored 817 publications receiving 114231 citations. Previous affiliations of Kari Alitalo include Mount Sinai Hospital, Toronto & Cornell University.
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Compositions and methods for treatment of lymphatic and venous vessel arterialization
TL;DR: In this paper, methods and compositions that may be used in disrupting the association of smooth muscle cells with lymphatic endothelial cells and in correcting the valvular dysfunction in veins and lymphatic vessels are presented.
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Cell transformation by c-Ha-rasVal12 oncogene is accompanied by a decrease in histone H1 zero and an increase in nucleosomal repeat length.
TL;DR: It is discovered that serum stimulation of normal and transformed cells, synchronized by serum starvation, induces rapid reversible changes in the structure of bulk chromatin that may be linked to transcriptional activation.
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Distinct roles of the meningeal layers in CNS autoimmunity
Arianna Merlini,Michael Haberl,Judith Strauss,Luisa Hildebrand,Nefiye Genc,Jonas Franz,Dmitri Chilov,Kari Alitalo,Cassandra Flügel-Koch,Christine Stadelmann,Alexander Flügel,Francesca Odoardi +11 more
TL;DR: An uneven involvement of the meningeal layers in CNS autoimmunity is demonstrated, in which effector T cell trafficking and activation are functionally confined to the leptomeninges, while the dura remains largely excluded from CNS autoimmune processes.
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Donor Heart Treatment With COMP‐Ang1 Limits Ischemia‐Reperfusion Injury and Rejection of Cardiac Allografts
Simo Syrjälä,Simo Syrjälä,Antti I. Nykänen,Antti I. Nykänen,R. Tuuminen,R. Tuuminen,Alireza Raissadati,Alireza Raissadati,Mikko A. I. Keränen,Mikko A. I. Keränen,Ralica Arnaudova,Ralica Arnaudova,Rainer Krebs,Rainer Krebs,G. Y. Koh,Kari Alitalo,Karl B. Lemström,Karl B. Lemström +17 more
TL;DR: Donor heart treatment with COMP‐Ang1 is suggested to have important clinical implications in the prevention of primary and subsequent long‐term injury and dysfunction in cardiac allografts.
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Effects of Zn2+ ions on protein phosphorylation in epithelial cell membranes.
TL;DR: The effects of Zn2+ ions on protein phosphorylation in membrane vesicles are complex and are not restricted to an inhibition of a single protein phosphatase or kinase.