scispace - formally typeset
K

Kari Alitalo

Researcher at University of Helsinki

Publications -  844
Citations -  122462

Kari Alitalo is an academic researcher from University of Helsinki. The author has contributed to research in topics: Angiogenesis & Vascular endothelial growth factor C. The author has an hindex of 174, co-authored 817 publications receiving 114231 citations. Previous affiliations of Kari Alitalo include Mount Sinai Hospital, Toronto & Cornell University.

Papers
More filters
Journal ArticleDOI

Mechanism of T cell proliferation in vivo: analysis of IL-2 receptor expression and activation of c-myc and c-myb oncogenes during lymphatic regeneration.

TL;DR: The results imply that the vigorous T cell proliferation during cyclophosphamide-induced lymphatic regeneration is independent of the IL-2/IL-2R hormone system, like T-cell precursor proliferation in the thymus, and is characterized by both high c-myb expression typical for thymocytes and highc-myc expression Typical for in vitro proliferation-activated T cells.
Posted ContentDOI

PROX1 transcription factor is a master regulator of myogenic and oncogenic features of rhabdomyosarcoma

TL;DR: It is demonstrated that PROX1 is needed for R MS cell stemness and growth in vitro, and for RMS tumor formation in mouse xenograft models, and that inhibiting this interaction could be a promising therapeutic approach.