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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Synthesis and Bioapplications of Ag 2 S Quantum Dots with Near-Infrared Fluorescence
TL;DR: In this article, the authors present various methods to synthesize NIR Ag2S QDs, and systematically discuss their applications in biosensing, bioimaging, and theranostics.
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Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB
TL;DR: As a blood-pool imaging agent, 68Ga-NEB is safe to use in the clinic, and the preliminary studies demonstrate the value of differentiating hepatic hemangioma from other benign or malignant focal hepatic lesions, warrant further clinical applications of NEB-based PET tracers.
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TAT-Modified Gold Nanoparticle Carrier with Enhanced Anticancer Activity and Size Effect on Overcoming Multidrug Resistance.
TL;DR: The data suggest that the larger AuNPs had more profound effect on overcoming MDR, which could effectively prevent drug efflux due to their size being much larger than that of the p-glycoprotein channel (9-25 Å).
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DNA–inorganic hybrid nanovaccine for cancer immunotherapy
Guizhi Zhu,Yijing Liu,Xiangyu Yang,Y.C. Kim,Huimin Zhang,Rui Jia,Hsien-Shun Liao,Albert J. Jin,Jing Lin,Maria A. Aronova,Richard D. Leapman,Zhihong Nie,Gang Niu,Xiaoyuan Chen +13 more
TL;DR: In this article, DNA-inorganic hybrid nanovaccines (hNVs) were used for efficient uptake into APCs, prolonged tumor retention, and potent immunostimulation and cancer immunotherapy.
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Synthesis and evaluation of new iRGD peptide analogs for tumor optical imaging
TL;DR: Two new near-infrared fluorescent iRGD conjugates were synthesized via the specific mercapto-maleimide reaction for tumor imaging and showed significant tumor localization in optical imaging of MDA-MB-435 tumor-bearing mice.