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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Suspension arrays based on nanoparticle-encoded microspheres for high-throughput multiplexed detection.
TL;DR: This review focuses on the current stock of nanoparticle-based barcodes as well as the manufacturing technologies required for their production, and aims to provide a comprehensive guide for the design of suspension arrays with the goal of improving their performance in areas such as multiplexing capacity, throughput, sensitivity, and cost effectiveness.
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Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots
TL;DR: DOTA–QD–VEGF primarily targets the tumor vasculature through a VEGF–VEGFR interaction and the success of this bifunctional imaging approach may render higher degree of accuracy for the quantitative targeted NIRF imaging in deep tissue.
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HSA Coated Iron Oxide Nanoparticles as Drug Delivery Vehicles for Cancer Therapy
Qimeng Quan,Jin Xie,Haokao Gao,Min Yang,Fan Zhang,Gang Liu,Xin Lin,Andrew Z. Wang,Henry S. Eden,Seulki Lee,Guixiang Zhang,Xiaoyuan Chen +11 more
TL;DR: D-HINPs showed a striking tumor suppression effect that was comparable to that of Doxil and greatly outperformed free Dox and can be readily extended to load other types of small molecules, making HINP a promising theranostic nanoplatform.
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Recent Advances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications.
TL;DR: Recent advances of contrast agents, applications, and signal enhancement strategies for PAI are introduced and perspectives of PAI for deep-tissue biomedical applications are provided.
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Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy
Peng Huang,Jing Lin,Jing Lin,Shouju Wang,Zhijun Zhou,Zhiming Li,Zhe Wang,Zhe Wang,Chunlei Zhang,Xuyi Yue,Xuyi Yue,Gang Niu,Min Yang,Daxiang Cui,Xiaoyuan Chen +14 more
TL;DR: This photo-theranostics owns good stability, high water dispersibility and solubility, non-cytotoxicity, and good biocompatibility, thus facilitating its biomedical applications, particularly for multi-modal optical, CT and photoacoustic imaging-guided PDT or sonodynamic therapy.