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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
Papers
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Journal ArticleDOI
64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics.
Chang-Tong Yang,Young-Seung Kim,Jianjun Wang,Lijun Wang,Jiyun Shi,Zibo Li,Xiaoyuan Chen,Ming Fan,Jian Jian Li,Shuang Liu +9 more
TL;DR: It was found that most (64)Cu radiotracers described in this study have significant advantages over (99m)Tc-Sestamibi for their high tumor/heart and tumor/muscle ratios.
Journal ArticleDOI
Yolk-shell nanovesicles endow glutathione-responsive concurrent drug release and T1 MRI activation for cancer theranostics
Dahai Liu,Zijian Zhou,Xinyu Wang,Hongzhang Deng,Lin Sun,Haixin Lin,Fei Kang,Yong Zhang,Zhantong Wang,Weijing Yang,Lang Rao,Kuikun Yang,Guocan Yu,Jianshi Du,Zheyu Shen,Xiaoyuan Chen +15 more
TL;DR: The obtained USD NVs showed a unique yolk-shell structure with restrained drug activity and quenched T1 MRI contrast ability which, on the other hand, can respond to glutathione (GSH) and lead to drug release and T1 contrast activation in a spatiotemporally concurrent manner.
Book ChapterDOI
Recent advances in nanoparticle-based nuclear imaging of cancers.
Avinash Srivatsan,Xiaoyuan Chen +1 more
TL;DR: There is a great need for the development of newer nanoparticles, which improve active targeting and quantify new biomarkers for early disease detection and possible prevention of cancer.
Journal ArticleDOI
18F-Alfatide II PET/CT for Identification of Breast Cancer: A Preliminary Clinical Study.
Jiang Wu,Shaohua Wang,Xianzhong Zhang,Zhaogang Teng,Jingjie Wang,Bryant C. Yung,Gang Niu,Hong Zhu,Guangming Lu,Xiaoyuan Chen +9 more
TL;DR: 18F-alfatide II is of good performance, but not superior to 18F-FDG in identifying breast cancer, and may have superiority in detecting breast cancer with strongly positive estrogen receptor expression and negative HER-2 expression.
Journal ArticleDOI
Molecular imaging of cell-based cancer immunotherapy
TL;DR: This review will summarize the application of multiple molecular imaging modalities in cell-based cancer immunotherapy by tracking cells and monitoring the therapeutic effects of transplanted cells in vivo.