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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Real Time, High Resolution Video Imaging of Apoptosis in Single Cells with a Polymeric Nanoprobe
Seulki Lee,Seulki Lee,Ki Young Choi,Ki Young Choi,Hyunjin Chung,Ju Hee Ryu,Aeju Lee,Aeju Lee,Heebeom Koo,In Chan Youn,Jae Hyung Park,In San Kim,Sang Yoon Kim,Xiaoyuan Chen,Seo Young Jeong,Ick Chan Kwon,Kwangmeyung Kim,Kuiwon Choi +17 more
TL;DR: The design platform of the Apo-NP is flexible and can be fine-tuned for a wide array of applications such as identification of caspase-related apoptosis in pathologies and for monitoring therapeutic efficacy of apoptotic drugs in cancer treatment.
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Integrin alpha v beta 3 antagonists for anti-angiogenic cancer treatment.
TL;DR: This review will focus on the key points and distinguishing factors for patents which use antibodies, RGD peptide, non-RGD peptides, peptidomimetics, and amine salts as αvβ3 antagonists for the prevention and/or treatment of cancer.
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Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.
Feng Cao,Zibo Li,Andrew S. Lee,Zhaofei Liu,Kai Chen,Hui Wang,Weibo Cai,Xiaoyuan Chen,Joseph C. Wu +8 more
TL;DR: By targeting alpha(v)beta(3) integrin, the ability of (64)Cu-DOTA-RGD4 to noninvasively visualize teratoma formation in vivo for the first time is shown.
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(18)F-Alfatide II PET/CT in healthy human volunteers and patients with brain metastases.
Chunjing Yu,Donghui Pan,Baoming Mi,Yuping Xu,Lixin Lang,Gang Niu,Min Yang,Weixing Wan,Xiaoyuan Chen +8 more
TL;DR: F-Alfatide II is a safe PET tracer with a favorable dosimetry profile that has potential value in finding brain metastases of different cancers as a biomarker of angiogenesis.
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Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy
TL;DR: Due to synergistic plasmonic photothermal properties of the complexes, the high/low PDT mode demonstrated improved efficacy over using single wavelength continuous laser irradiation, and no significant loss in viability was observed in cells exposed to free AlPcS4 photosensitizer under the same irradiation conditions.