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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Firefly luciferase-based dynamic bioluminescence imaging: a noninvasive technique to assess tumor angiogenesis.
Amy Sun,Lewis C. Hou,Tiffany Prugpichailers,Jason Dunkel,Maziyar A. Kalani,Maziyar A. Kalani,Xiaoyuan Chen,M. Yashar S. Kalani,Victor Tse,Victor Tse +9 more
TL;DR: In this paper, a non-invasive in-vivo technique was used to monitor tumor growth and permeability of the blood-brain barrier in an experimental model of glioma in mice.
Journal ArticleDOI
One-Pot Two-Step Radiosynthesis of a New 18F-Labeled Thiol Reactive Prosthetic Group and Its Conjugate for Insulinoma Imaging
Xuyi Yue,Xuefeng Yan,Xuefeng Yan,Chenxi Wu,Chenxi Wu,Gang Niu,Ying Ma,Orit Jacobson,Baozhong Shen,Dale O. Kiesewetter,Xiaoyuan Chen +10 more
TL;DR: [18F]FNEM-Cys40-exendin-4 showed specific targeting of glucagon-like peptide 1 receptor (GLP-1R) positive insulinomas and comparable imaging results to the recently reported [18F].
Journal ArticleDOI
Noninvasive monitoring of pulmonary fibrosis by targeting matrix metalloproteinases (MMPs)
TL;DR: MMPs may play an important role in PF development and the MMP-P12 probe could be a promising tool for PF detection, even at an early stage of the disease as well as an indicator of therapy response.
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Tuning the properties of atomically precise gold nanoclusters for biolabeling and drug delivery
TL;DR: A structure-determined gold-levonorgestrel nanocluster, Au10(C 21H27O2)10 (Au10NC), has been obtained via solvent induced crystal transformation from Au8(C21H27 O2)8 (au8NC), accompanied by a fluorescence color change from green to yellow.
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Hierarchical Assembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular Nanofibril Self-Supportive Scaffolds for Stem Cell Differentiation.
Zhe Wang,Fuwu Zhang,Zhantong Wang,Yijing Liu,Xiao Fu,Albert J. Jin,Bryant C. Yung,Wei Chen,Jing Fan,Xiangyu Yang,Gang Niu,Xiaoyuan Chen +11 more
TL;DR: This study is a successful attempt to entirely use bioactive molecules for bottom-up self-assembly of new biomaterials mimicking the ECM to directly impact cell behaviors and provides a new avenue in biomaterial design to advance tissue engineering and cell delivery.