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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Quantitative Analysis and Parametric Imaging of 18F-Labeled Monomeric and Dimeric RGD Peptides Using Compartment Model
Ning Guo,Ning Guo,Lixin Lang,Haokao Gao,Gang Niu,Dale O. Kiesewetter,Qingguo Xie,Xiaoyuan Chen +7 more
TL;DR: Kinetic parameters were demonstrated to be valuable for separating specific and non-specific binding and may allow more sensitive and detailed quantification than simple standardized uptake value analysis.
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Oxidative stress-driven DR5 upregulation restores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles in colorectal cancer
Yesi Shi,Junqing Wang,Jingyi Liu,Gan Lin,Fengfei Xie,Xin Pang,Yihua Pei,Yi Cheng,Yang Zhang,Zhongning Lin,Zhengyu Yin,Xiaomin Wang,Gang Niu,Xiaoyuan Chen,Gang Liu +14 more
TL;DR: In the study of colorectal cancer patient-derived xenograft models, it is found that the NanoTRAIL treatment could significantly improve the survival outcome with consistent ROS-dependent autophagy-assisted DR5 upregulation and tumor apoptosis.
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Functional T cell activation by smart nanosystems for effective cancer immunotherapy
TL;DR: Applications of nanosystem-mediated immunotherapy for functional T cell activation, including formation of artificial antigen presenting cells, cancer nanovaccination, tumor microenvironment modulation, and combination therapy are reviewed.
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Organic high ionic strength aqueous two-phase solvent system series for separation of ultra-polar compounds by spiral high-speed counter-current chromatography
TL;DR: A new solvent series which can be applied for the separation of highly polar compounds, composed of 1-butanol, ethanol, saturated ammonium sulfate and water at various volume ratios and consists of a series of 10 steps according to the polarity of the solvent system.
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Nanobiohybrids: A Synergistic Integration of Bacteria and Nanomaterials in Cancer Therapy
TL;DR: It is demonstrated that the bacteria-based nanobiohybrids have the potential to provide a targeted and effective approach for cancer treatment.