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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
Accelerating the Translation of Nanomaterials in Biomedicine.
Samir Mitragotri,Daniel G. Anderson,Xiaoyuan Chen,Edward Kai-Hua Chow,Dean Ho,Alexander V. Kabanov,Jeffrey M. Karp,Kazunori Kataoka,Chad A. Mirkin,Sarah Hurst Petrosko,Jinjun Shi,Molly M. Stevens,Shouheng Sun,Swee Hin Teoh,Subbu S. Venkatraman,Younan Xia,Shutao Wang,Zhen Gu,Chenjie Xu +18 more
TL;DR: Nano Focus as discussed by the authors discusses the current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic, by highlighting a handful of successful examples.
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Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody
TL;DR: The success of EGFR-positive tumor imaging using 64Cu-DOTA-cetuximab can be translated into the clinic to characterize the pharmacokinetics, to select the right population of patients for EGFR -targeted therapy, and to monitor the therapeutic efficacy of anti-EGFR treatment.
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Self-Assembly of Amphiphilic Plasmonic Micelle-Like Nanoparticles in Selective Solvents
Jie He,Xinglu Huang,Yanchun Li,Yijing Liu,Taarika Babu,Maria A. Aronova,Shouju Wang,Zhongyuan Lu,Xiaoyuan Chen,Zhihong Nie +9 more
TL;DR: The self-assembly, modeling, and applications of APMN assemblies in selective solvents resulted in strong absorption in near-infrared range due to the remarkable plasmonic coupling of Au cores, thus facilitating their biomedical applications in bioimaging and photothermal therapy of cancer.
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Efficient Nanovaccine Delivery in Cancer Immunotherapy
TL;DR: Aside from peptide antigens, antigen-encoding mRNA for cancer immunotherapy delivered by nanovaccine will also be discussed, and the intracellular release of vaccine and cross-presentation of antigen can be fine-tuned via nanovACCine engineering.
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Integrin αvβ3-targeted cancer therapy
TL;DR: The role of integrin αvβ3 in angiogenesis is reviewed, recent progress in the use ofIntegrin α vβ3 antagonists and integrin‐targeted delivery systems as potential cancer therapeutics are presented, and future perspectives are discussed.