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Xiaoyuan Chen

Researcher at National University of Singapore

Publications -  1270
Citations -  115993

Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.

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A cyclic HSV1-TK reporter for real-time PET imaging of apoptosis

TL;DR: A unique molecularly engineered cyclic herpes simplex virus type 1–thymidine kinase reporter containing a caspase-3 recognition domain as the switch for real-time apoptosis PET imaging is described, showing the high sensitivity of this reporter in dynamic and quantitative imaging of apoptosis in living subjects.
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High temperature pyrolysis of 2-methyl furan

TL;DR: Simulations of the experimental results with a model that incorporated the theoretical predictions of reaction paths failed to reproduce the experimental data, so the resulting model provides good simulations of the complete set of experimental data.
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Improving cell-based therapies by nanomodification

TL;DR: In this review, some novel cell surface engineering and intracellular nanoconjugation strategies are summarized and it is believed that these novel cell-material complexes can have great potentials for biomedical applications.
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Novel Method for Radiolabeling and Dimerizing Thiolated Peptides Using (18)F-Hexafluorobenzene.

TL;DR: F-HFB can be efficiently incorporated into thiol-containing peptides at room temperature to provide novel imaging agents and demonstrated integrin receptor specific binding, cellular uptake, and in vivo tumor accumulation.
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Depth-Resolved Enhanced Spectral-Domain OCT Imaging of Live Mammalian Embryos Using Gold Nanoparticles as Contrast Agent

TL;DR: Results show that after GNR treatment, more accurate spatial localization and better contrasting of the borders among organs can be observed on E9.5 and E10.5 mouse embryos, which provide a promising strategy for monitoring organ development and detecting congenital structural abnormalities in mice.