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Xiaoyuan Chen

Researcher at National University of Singapore

Publications -  1270
Citations -  115993

Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.

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Activation of sulfite by metal-organic framework-derived cobalt nanoparticles for organic pollutants removal.

TL;DR: In this article , the cobalt nanoparticles embedded in nitrogen-doped graphite layers (Co@NC), were used to activate SO32- for removal of Methyl Orange in aqueous solution.
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DCE-MRI-Derived Parameters in Evaluating Abraxane-Induced Early Vascular Response and the Effectiveness of Its Synergistic Interaction with Cisplatin.

TL;DR: Abraxane-mediated permeability variations in tumor vasculature can be quantitatively visualized by DCE-MRI, making this a useful method for studying the effects of early cancer treatment, especially the early vascular response.
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68Ga-NOTA-Exendin-4 PET/CT in Localization of an Occult Insulinoma and Appearance of Coexisting Esophageal Carcinoma.

TL;DR: A 61-year-old woman with biochemically proven endogenous hyperinsulinemic hypoglycemia and negative conventional imaging underwent 68Ga-NOTA-exendin-4 PET/CT for localization of insulinoma, and focal intense radioactivity in the tail of the pancreas was observed that was subsequently confirmed as insulinoma pathologically after surgical resection.
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Endocytosis-Enabled Construction of Silica Nanochannels Crossing Living Cell Membrane for Transmembrane Drug Transport

TL;DR: This work not only clarifies the cellular interaction between 1D nanomaterials and living cells, but also pioneers the use of natural endocytosis of 1Dnanowires for constructing ATC, resulting in enhanced drug delivery efficacy and decreased the half maximal inhibitory concentration.
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A paradigm of cancer immunotherapy based on 2-[18F]FDG and anti-PD-L1 mAb combination to enhance the anti-tumor effect.

TL;DR: It is hypothesized that 2-[18F]FDG could induce PD-L1 expression change and create an immune-favorable microenvironment for tumor immunotherapy and has the potential to expand the traditional tumor theranostics.