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Xiaoyuan Chen
Researcher at National University of Singapore
Publications - 1270
Citations - 115993
Xiaoyuan Chen is an academic researcher from National University of Singapore. The author has contributed to research in topics: Photothermal therapy & Medicine. The author has an hindex of 149, co-authored 994 publications receiving 89870 citations. Previous affiliations of Xiaoyuan Chen include Brown University & University of Southern California.
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Journal ArticleDOI
N -Succinimidyl 4-[ 18 F]-fluoromethylbenzoate-labeled dimeric RGD peptide for imaging tumor integrin expression
Weihua Li,Lixin Lang,Gang Niu,Ning Guo,Ying Ma,Dale O. Kiesewetter,Baozhong Shen,Xiaoyuan Chen +7 more
TL;DR: N-succinimidyl 4-[18F]-fluoromethylbenzoate ([18F]SFMB) prosthetic group can be a good alternative for labeling RGD peptides to image αvβ3 integrin expression and for labeling other peptides.
Journal ArticleDOI
Biomedical Applications: Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer-Functionalized Gold Nanostars (Adv. Mater. 22/2013)
Shouju Wang,Shouju Wang,Peng Huang,Peng Huang,Liming Nie,Liming Nie,Ruijun Xing,Dingbin Liu,Zhe Wang,Zhe Wang,Jing Lin,Jing Lin,Shouhui Chen,Gang Niu,Guangming Lu,Xiaoyuan Chen +15 more
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Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma
Lucia Martiniova,Susannah Cleary,Edwin W. Lai,Dale O. Kiesewetter,Jurgen Seidel,Linda F. Dawson,Jacqueline K. Phillips,Jacqueline K. Phillips,David Thomasson,Xiaoyuan Chen,Graeme Eisenhofer,James F. Powers,Richard Kvetnansky,Karel Pacak +13 more
TL;DR: Subcutaneous tumors were localized only with [(18)F]-DOPA, a finding that may reflect differences in expression of VMAT1 and VMAT2, perhaps similar to some patients with pheochromocytoma where [( 18)F]DOPA provides better visualization of lesions than [(18]F]-DA.
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Evaluation of fluorine-labeled gastrin-releasing peptide receptor (GRPR) agonists and antagonists by LC/MS
Ying Ma,Min Yang,Haokao Gao,Gang Niu,Yongjun Yan,Lixin Lang,Dale O. Kiesewetter,Xiaoyuan Chen +7 more
TL;DR: This study developed strategies to evaluate the in vitro receptor mediated cell uptake and metabolic profile of the various GRPR agonists and antagonists and identified the metabolites produced by rat hepatocytes and quantitatively analyzed the uptake and internalization of the ligands in PC-3 human prostate cancer cells.
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Visualization of Copper Metabolism by 64CuCl2-PET
Hui Wang,Xiaoyuan Chen +1 more
TL;DR: Two stable isotopes of copper, 63Cu and 65Cu, have been proven to be very effective in providing information related to copper absorption, bioavailability, and excretion patterns, and it is demonstrated that the rate of the uptake of copper by the liver of patients with Wilsons’s disease varies with the state of the illness.