Kuvempu University

About: Kuvempu University is a education organization based out in Shimoga, India. It is known for research contribution in the topics: Cyclic voltammetry & Carbon paste electrode. The organization has 1575 authors who have published 2210 publications receiving 39755 citations. The organization is also known as: KU.

Optimized Solid-State Fermentation Medium Enhances the Multienzymes Production from Penicillium citrinum and Aspergillus clavatus

Abstract: Filamentous fungi play an important role in the production of a range of useful extracellular hydrolytic enzymes for wide industrial applications. The Western Ghats region is known for its rich microbial biodiversity and could be a potential source of several useful fungi that could be exploited for the production of industrially important enzymes. From this soil, we aimed at the isolation of multienzyme producing fungi, optimization of the culture conditions using solid-state fermentation (SSF), partial purification of enzymes and characterization by zymography. Out of seven fungal strains, two isolates, namely Penicillium citrinum and Aspergillus clavatus, were found to produce amylase and cellulase enzymes maximally. The effect of different physicochemical parameters on the production of amylase and cellulase was investigated and the maximum production of multienzymes was achieved in wheat bran substrate. The newly formulated and optimized medium increased the multienzyme production in P. citrinum and A. clavatus as compared to medium with individually optimized parameters. Further, for the first time, different isoforms of amylase and cellulase have been identified from P. citrinum and A. clavatus by zymography. In summary, the present study showed that the filamentous fungi can utilize the industrial waste product such as wheat bran as the substrate for multienzymes production by SSF and could be a promising source of enzymes for biotechnological applications.

An efficient Bi(NO3)3 · 5H2O catalyzed multi component one-pot synthesis of novel Naphthyridines

Abstract: An efficient and environmentally friendly multicomponent synthesis of substituted 1,8-naphthyridines catalyzed by bismuth(III) nitrate pentahydrate [Bi(NO3)3 · 5H2O] under solvent-free microwave irradiation is described. This procedure has such advantages as short reaction time, high yields, and simple workup. The catalyst could be reused several times, keeping its initial activity recycled reactions.