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Open AccessJournal ArticleDOI

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Ting Shi, +138 more
- 02 Sep 2017 - 
- Vol. 390, Iss: 10098, pp 946-958
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TLDR
In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
About: 
This article is published in The Lancet.The article was published on 2017-09-02 and is currently open access. It has received 1470 citations till now. The article focuses on the topics: Disease burden & Case fatality rate.

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Citations
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Journal ArticleDOI

Respiratory Syncytial Virus Disease: Immunoprophylaxis Policy Review and Public Health Concerns in Preterm and Young Infants.

Suzanne Staebler, +1 more
- 01 Feb 2021 - 
TL;DR: The critical roles and strategies of advocacy groups and nurses in providing the maximum protection with RSV immunoprophylaxis to all high-risk and label-eligible preterm infants are discussed.
Journal ArticleDOI

The Burden of Respiratory Syncytial Virus in Children Under 2 Years of Age in a Rural Community in Maharashtra, India.

Ashish Satav, +10 more
- 02 Sep 2021 - 
TL;DR: In this paper, the authors performed active surveillance in the community and hospital setting for the population of 93 tribal villages in Melghat, Central India, over four respiratory seasons and found high rates of RSV-associated LRTI were found in preterm and term infants beyond 6 months of age, extending into the second year of life.
Posted ContentDOI

Assessing the utility of minority variant composition in elucidating RSV transmission pathways

George Githinji, +13 more
- 12 Sep 2018 - 
TL;DR: It is reported that RSV-A infections are characterized by low frequency diversity that occurs across the genome, and interpretation of minor variant patterns was tractable only for small household outbreaks.
Journal ArticleDOI

Development and comparison of three cell-based potency assays for anti-respiratory syncytial virus monoclonal antibody.

Dengyun Sun, +6 more
- 27 Oct 2021 - 
TL;DR: In this article, the authors evaluated three RSV neutralization assays to test the potency of MK-1654, including an imaging-based virus reduction neutralization test (VRNT) and two reporter virus-based assays (RSV-GFP and RSV-NLucP).
Journal ArticleDOI

Disease severity of respiratory syncytial virus (RSV) infection correlate to a novel set of five amino acid substitutions in the RSV attachment glycoprotein (G) in China

Wanwei Li, +8 more
- 01 May 2020 - 
TL;DR: A specific set of five amino acid substitutions was found in China and further analysis showed that disease severity was associated with these alterations, which will provide valuable information for the pathogenic mechanism and vaccine development of RSV.
References
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Journal ArticleDOI

Meta-Analysis in Clinical Trials*

Rebecca DerSimonian, +3 more
- 01 Sep 1986 - 
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Journal ArticleDOI

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
Journal ArticleDOI

Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

Lei Liu, +8 more
- 31 Jan 2015 - 
TL;DR: The authors' projection results provide concrete examples of how the distribution of child causes of deaths could look in 15-20 years to inform priority setting in the post-2015 era.
Journal ArticleDOI

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

Harish Nair, +24 more
- 01 May 2010 - 
TL;DR: Mortality data suggest that RSV is an important cause of death in childhood from ALRI, after pneumococcal pneumonia and Haemophilus influenzae type b, and the development of novel prevention and treatment strategies should be accelerated as a priority.
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