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Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Ting Shi, +138 more
- 02 Sep 2017 - 
- Vol. 390, Iss: 10098, pp 946-958
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TLDR
In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
About: 
This article is published in The Lancet.The article was published on 2017-09-02 and is currently open access. It has received 1470 citations till now. The article focuses on the topics: Disease burden & Case fatality rate.

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The Etiology of Pneumonia in Zambian Children: Findings From the Pneumonia Etiology Research for Child Health (PERCH) Study

Lawrence Mwananyanda, +18 more
- 01 Sep 2021 - 
TL;DR: A case-control study of HIV-uninfected children age 1-59 months admitted with World Health Organization-defined severe or very severe pneumonia to a large tertiary care hospital in Lusaka, Zambia as mentioned in this paper showed that the overall mortality was 16.0% (82 deaths).
Journal ArticleDOI

The impact of a digital wheeze detector on parental disease management of pre-school children suffering from wheezing—a pilot study

Stephanie Dramburg, +3 more
- 09 Oct 2021 - 
TL;DR: In this paper, a single-armed pilot study enrolled patients with a doctor's diagnosis of wheezing aged 9 to 72 months, and participants were asked to use a digital wheeze detector (WheezeScan, Omron Healthcare, Japan) 2×/day for 30 days and record the child's respiratory symptoms, detection of asthma, and medication intake via an eDiary app.
Journal ArticleDOI

A landscape review of the published research output relating to respiratory syncytial virus (RSV) in North & Central America and Europe between 2011-2015

Amir Kirolos, +5 more
- 01 Jun 2019 - 
TL;DR: This review identifies key regions and research institutions which contributed to RSV-related research during 2011-2015 as well as the donor agencies which supported this research.
Journal ArticleDOI

CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newborns

Simon D. van Haren, +18 more
- 02 Aug 2022 - 
TL;DR: In this paper , the authors apply quantitative phosphoproteomics to human dendritic cells and reveal a role for Protein Kinase C-δ for enhanced Th1 cytokine production in neonatal dendocyte cells and identify signaling events resulting in antigen cross-presentation.
Journal ArticleDOI

Ephedrae Herba and Cinnamomi Cortex interactions with G glycoprotein inhibit respiratory syncytial virus infectivity

Aya Fujikane, +6 more
- 25 Jan 2022 - 
TL;DR: Maoto components, Ephedrae Herba (EH) and Cinnamomi Cortex (CC), specifically interacted with the central conserved domain (CCD) of G protein, and also found that this interaction blocked viral attachment to the cellular receptor CX3CR1 as discussed by the authors .
References
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Journal ArticleDOI

Meta-Analysis in Clinical Trials*

Rebecca DerSimonian, +3 more
- 01 Sep 1986 - 
TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Journal ArticleDOI

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
Journal ArticleDOI

Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

Lei Liu, +8 more
- 31 Jan 2015 - 
TL;DR: The authors' projection results provide concrete examples of how the distribution of child causes of deaths could look in 15-20 years to inform priority setting in the post-2015 era.
Journal ArticleDOI

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

Harish Nair, +24 more
- 01 May 2010 - 
TL;DR: Mortality data suggest that RSV is an important cause of death in childhood from ALRI, after pneumococcal pneumonia and Haemophilus influenzae type b, and the development of novel prevention and treatment strategies should be accelerated as a priority.
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