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Open AccessJournal ArticleDOI

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Ting Shi, +138 more
- 02 Sep 2017 - 
- Vol. 390, Iss: 10098, pp 946-958
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TLDR
In this paper, the authors estimated the incidence and hospital admission rate of RSV-associated acute lower respiratory infection (RSV-ALRI) in children younger than 5 years stratified by age and World Bank income regions.
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This article is published in The Lancet.The article was published on 2017-09-02 and is currently open access. It has received 1470 citations till now. The article focuses on the topics: Disease burden & Case fatality rate.

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Pediatric lung imaging features of COVID-19: A systematic review and meta-analysis.

TL;DR: This systematic review and meta‐analysis is to provide the first comprehensive summary of the findings of published studies thus far describing COVID‐19 lung imaging data in the pediatric population.
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Evaluating the next generation of RSV intervention strategies: a mathematical modelling study and cost-effectiveness analysis.

TL;DR: In a setting with seasonal RSV epidemiology, maternal protection conferred to newborns is also seasonal, an assumption not previously incorporated in transmission models of RSV, which suggests seasonal programmes rather than year-round intervention programmes are always optimal.
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Current Animal Models for Understanding the Pathology Caused by the Respiratory Syncytial Virus.

TL;DR: The various applications of animal models to the study of hRSV-induced disease and the advantages and disadvantages of each model are discussed, highlighting the potential of eachmodel to elucidate different features of the pathology caused by the h RSV infection.
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Estimating the impact of multiple immunization products on medically-attended respiratory syncytial virus (RSV) infections in infants.

TL;DR: A tool for practicing public health officials to estimate the impact of immunization strategies on RSV-associated MA lower respiratory tract infections (LRTIs) in various healthcare settings among infants <12 months underscores the potential for anticipated products to reduce serious RSV illness.
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Mortality Associated With Acute Respiratory Infections Among Children at Home.

TL;DR: Social vulnerabilities underlie at-home mortality due to acute respiratory infections in children aged <5 years in the developing world and are similar to those reported for hospitalized children.
References
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Journal ArticleDOI

Meta-Analysis in Clinical Trials*

TL;DR: This paper examines eight published reviews each reporting results from several related trials in order to evaluate the efficacy of a certain treatment for a specified medical condition and suggests a simple noniterative procedure for characterizing the distribution of treatment effects in a series of studies.
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Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
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Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis.

TL;DR: The authors' projection results provide concrete examples of how the distribution of child causes of deaths could look in 15-20 years to inform priority setting in the post-2015 era.
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